The role of suburothelial myofibroblasts and afferent nerve fibres as mediators of bladder sensation and as possible drug targets in detrusor overactivity.

Antragsteller Professor Dr. Alexander Roosen

Fachliche Zuordnung Reproduktionsmedizin, Urologie

Förderung Förderung von 2006 bis 2009

Projektkennung Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 32643384

Erstellungsjahr 2008

Zusammenfassung der Projektergebnisse

Keine Zusammenfassung vorhanden

(2007). Urothelial targets in the overactive bladder. Journal für Urologie und Urogynäkologie, 14: 20-23
Fry CH, Roosen A
Adreno-muscarinic synergy in the bladder trigone: Calcium-dependent and -independent mechanisms. Cell Calcium. 2008 Jun 30
Roosen A, Fry CH, Sui G, Wu C
Characteristics of Spontaneous Activity in the Bladder Trigone. Eur Urol. 2008 Jun 20 [Epub ahead of print]
Roosen A, Wu C, Sui G, Chowdhury RA, Patel PM, Fry CH
Editorial Comment on: Bladder Angiotensin-II Receptors: Characterization and Alteration in Bladder Outlet Obstruction. Eur Urol. 2008 Mar 19
Roosen A
Editorial Comment on: TGF-beta1 Inhibits Cx43 Expression and Formation of Functional Syncytia in Cultured Smooth Muscle Cells from Human Detrusor. Eur Urol. 2008 Apr 3
Roosen A, Fry CH
Modulation of bladder myofibroblast activity: implications for bladder function. Am J Physiol Renal Physiol. 2008 Sep; 295(3): F688-97
Sui GP, Wu C, Roosen A, Ikeda Y, Kanai AJ, Fry CH
Synergistic effects in neuromuscular activation and calcium-sensitisation in the bladder trigone. BJU Int. 2008 Mar;101(5):610-4
Roosen A, Wu C, Sui GP, Fry CH