Controlling stealth and barrier breaking behavior: Hybrid protein nanofibers and POxylation on polymeric nanoparticles with structurally tailored thermal properties (A06)

• Subject Area: Polymer Materials
• Term: since 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 316213987

By modulating the surface of polyester nanoparticles with poly(2-oxazoline)s (POx) and hybrid protein nanofibers (HPNF), the project will investigate the influence of these attached materials on the internal structure of the nanoparticle core through assessment of the thermal and mechanical properties. Depending on their structure and functionality, the POx and HPNF will also induce stealth or barrier breaking properties to the nanoparticles and serve as platform for the attachment of targeting ligands.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1278: Polymer-based nanoparticle libraries for targeted anti-inflammatory strategies
• Applicant Institution: Friedrich-Schiller-Universität Jena
• Project Heads: Professor Dr. Klaus D. Jandt; Professor Dr. Ulrich S. Schubert