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EXC 257:  NeuroCure - Towards a Better Outcome of Neurological Disorders

Subject Area Neurosciences
Term from 2007 to 2018
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 39052203
 
Final Report Year 2019

Final Report Abstract

Neurological and psychiatric disorders pose a massive burden to society, and our understanding of the underlying molecular and pathophysiological mechanisms is limited. At the same time, the translation, or transfer, of knowledge from basic research into clinical application has proven difficult. For this reason, NeuroCure has set out to narrow the current gap between basic and clinical neuroscience and thereby promote the development and application of new therapies and diagnostic tools. To achieve the critical mass for excellent research in the neurosciences, we appointed more than 25 outstanding scientists, including excellent female researchers and promising early career scientists. Their integration into the existing scientific environment was promoted by collaborative projects with a strong interdisciplinary and translational focus. In addition, visiting fellow programs enabled us to recruit many international experts, including Nobel Laureates, for research stays in Berlin. Excellent research is also driven by the development of new technologies. NeuroCure therefore established several technology platforms that provide state-of-the-art instruments and expertise, e. g. in the areas of imaging and automated behavioral analysis of animal models of various diseases. In addition, the NeuroCure Clinical Research Center, a fully equipped outpatient facility, provides full administrative and logistic support for high-quality clinical trials. Successful translation additionally requires a strong interdisciplinary mind-set. We therefore developed an international MSc/PhD program with a focus on interdisciplinary research and translation, combining comprehensive training with advice from experienced neuroscientists across disciplines. Moreover, in line with our commitment to advance equal opportunity within the Cluster and our partner institutions, NeuroCure promoted the recruitment of excellent female scientists to higher academic positions through diverse measures. Finally, in cooperation with the Charité and our partner institutions, we overcame institutional and administrative barriers and established the Einstein Center for Neurosciences Berlin. Through these extensive measures, NeuroCure has substantially strengthened collaborations between basic and clinical researchers. The success of the Cluster is documented by many high-impact publications and a significant increase in collaborative research grants in Berlin. In the future, we will continue to use this momentum to secure Berlin’s position at the forefront of translational neuroscience.

Link to the final report

https://doi.org/10.2314/KXP:1698804903

Publications

 
 

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