Disturbed B cell homeostasis of B cells in SLE: Delineation of intrinsic signaling abnormalities

• Applicant: Professor Dr. Thomas Dörner
• Subject Area: Rheumatology
• Term: from 2017 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 390780177

• Final Report Year: 2021

No abstract available

Publications

• (2018). Anti-interleukin-6 signalling therapy rebalances the disrupted cytokine production of B cells from patients with active rheumatoid arthritis. Eur J Immunol 48, 194-203
  Fleischer, Sarah; Ries, Stefanie; Shen, Ping; Lheritier, Alix; Cazals, Frédéric; Burmester, Gerd. R.; Dörner, Thomas & Fillatreau, Simon
  
• (2019). Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases. Front Immunol 10, 2136
  Weißenberg, Sarah Y.; Szelinski, Franziska; Schrezenmeier, Eva; Stefanski, Ana-Luisa; Wiedemann, Annika; Rincon-Arevalo, Hector; Welle, Anna; Jungmann, Annemarie; Nordström, Karl; Walter, Jörn; Imgenberg-Kreuz, Juliana; Nordmark, Gunnel; Rönnblom, Lars; Bachali, Prathyusha; Catalina, Michelle D.; Grammer, Amrie C.; Lipsky, Peter E.; Lino, Andreia C. & Dörner, Thomas
  
• (2020). Therapeutic implications of the anergic/postactivated status of B cells in systemic lupus erythematosus. RMD Open 6
  Dörner, Thomas; Szelinski, Franziska; Lino, Andreia C. & Lipsky, Peter E.
  
• (2021). Toll-like receptor signalling in B cells during systemic lupus erythematosus.Nat Rev Rheumatol. 17:98-108
  Fillatreau, Simon; Manfroi, Benoît & Dörner, Thomas