GSC 249:  The Hartmut Hoffmann-Berling International Graduate School of Molecular and Cellular Biology

• Subject Area: Basic Research in Biology and Medicine
• Term: from 2007 to 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 39338214

• Final Report Year: 2019

Final Report Abstract

The Hartmut Hoffmann-Berling International Graduate School of Molecular & Cellular Biology Heidelberg, renamed to Heidelberg Biosciences International Graduate School (henceforth “HBIGS”) in 2018, was founded in Oct 2007 with the vision to attract the best and brightest doctoral researchers from around the world to pursue doctoral studies at Heidelberg University. Since then, HBIGS has developed into the largest and most visible structured graduate programme for life sciences at Heidelberg University. During the initial funding period, HBIGS implemented an innovative approach to doctoral training, with a strong emphasis on interdisciplinarity, a structured PhD program, shared supervision by thesis advisory committees, a vocational concept, the integration of an MD/PhD program, and the implementation of measures to promote women and scientists with young families. During the second funding period, HBIGS has evolved from a thematically focused graduate school into a graduate school for molecular life science that embraces and serves the entire life science community at Heidelberg University as well as non-university institutions. As such HBIGS has managed more than a dozen national and international graduate programs. HBIGS represents a truly international graduate school with more than 40% international doctoral researchers and more than 80% international applicants. Indicators of academic excellence of the HBIGS student body are an impressive publication record of more than 1,500 peer-reviewed scientific articles authored by our doctoral researchers, a mean time to degree of 4.1 years, a low drop-out rate 7%, a balanced gender distribution, and excellent employment opportunities for graduates.

Publications

• (2010). Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction. Nat Cell Biol
  Mardin BR, Lange C, Baxter JE, Hardy T, Scholz SR, Fry AM, Schiebel E
  
• (2010). Mutations detected in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation. Nat Genet
  Berkel S, Marshall CR, Weiss B, Howe J, Roeth R, Moog U, Endris V, Roberts W, Szatmari P, Pinto D, Bonin M, Riess A, Engels H, Sprengel R, Scherer SW, Rappold GA
  
• (2010). Stimulation of Cell Adhesion at nanostructured Teflon Interfaces. Advanced Materials
  Kruss S, Wolfram T, Martin R, Neubauer S, Kessler H, Spatz JP
  
• (2011). Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia. Cell Metab
  Kulozik P, Jones A, Mattijssen F, Rose AJ, Reimann A, Strzoda D, Kleinsorg S, Raupp C, Kleinschmidt J, Müller-Decker K, Wahli W, Sticht C, Gretz N, von Loeffelholz C, Stockmann M, Pfeiffer A, Stöhr S, Dallinga-Thie GM, Nawroth PP, Berriel Diaz M, Herzig S
  
• (2011). Mapping of Signalling Networks through Synthetic Genetic Interaction Analysis by RNAi. Nature Methods
  Horn T, Sandmann T, Fischer B, Axelsson E, Huber W, Boutros M
  
• (2011). Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment. Cell Host Microbe
  Reiss S, Rebhan I, Backes P, Romero-Brey I, Erfle H, Matula P, Kaderali L, Poenisch M, Blankenburg H, Hiet MS, Longerich T, Diehl S, Ramirez F, Balla T, Rohr K, Kaul A, Bühler S, Pepperkok R, Lengauer T, Albrecht M, Eils R, Schirmacher P, Lohmann V
  
• (2012). An extended gamma-tubulin ring functions as a stable platform in microtubule nucleation. J Cell Biol
  Erlemann S, Neuner A, Gombos L, Gibeaux R, Anthony C, Schiebel E
  
• (2012). Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication. Hepatology
  Metz P, Dazert E, Ruggieri A, Mazur J, Kaderali L, Kaul A, Zeuge U, Trippler M, Lohmann V, Binder M, Frese M, Bartenschlager R
  
• (2012). Rif2 Promotes a Telomere Fold-Back Structure through Rpd3L Recruitment in Budding Yeast. PLoS Genet
  Poschke H, Dees M, Chang M, Amberkar S, Kaderali L, Rothstein R, Luke B
  
• (2012). Site-specific terminal and internal labeling of RNA by poly(A) polymerase tailing and copper-catalyzed or copper-free strainpromoted click chemistry. Nucleic Acids Res
  Winz ML, Samanta A, Benzinger D, Jäschke A
  
• (2012). Structure and Dynamics of the ATP-Bound Open Conformation of Hsp70 Chaperones. Mol Cell
  Kityk R, Kopp J, Sinning I, Mayer MP
  
• (2012). The cisregulatory code of Hox function in Drosophila. EMBO J
  Sorge S, Ha N, Polychronidou M, Friedrich J, Bezdan D, Kaspar P, Schaefer MH, Ossowski S, Henz SR, Mundorf J, Rätzer J, Papagiannouli F, Lohmann I
  
• (2012). Ubiquitin-Dependent Intramembrane Rhomboid Protease Promotes ERAD of Membrane Proteins. Mol Cell
  Fleig L, Bergbold N, Sahasrabudhe P, Geiger B, Kaltak L, Lemberg MK
  
• (2013). Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B. Hepatology
  Esser-Nobis K, Romero-Brey I, Ganten TM, Gouttenoire J, Harak C, Klein R, Schemmer P, Binder M, Schnitzler P, Moradpour D, Bartenschlager R, Polyak SJ, Stremmel W, Penin F, Eisenbach C, Lohmann V
  
• (2013). Detecting endogenous SUMO targets in mammalian cells and tissues. Nat Struct Mol Biol
  Becker J, Barysch SV, Karaca S, Dittner C, Hsiao HH, Berriel Diaz M, Herzig S, Urlaub H, Melchior F
  
• (2013). Posttranscriptional regulation of the trypanosome heat shock response by a zinc finger protein. PLoS Pathog
  Droll D, Minia I, Fadda A, Singh A, Stewart M, Queiroz R, Clayton C
  
• (2013). Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence. Nat Struct Mol Biol
  Balk B, Maicher A, Dees M, Klermund J, Luke-Glaser S, Bender K, Luke B
  
• (2013). The Lipid Kinase Phosphatidylinositol-4 Kinase III Alpha Regulates the Phosphorylation Status of Hepatitis C Virus NS5A. PLoS Pathog
  Reiss S, Harak C, Romero-Brey I, Radujkovic D, Klein R, Ruggieri A, Rebhan I, Bartenschlager R, Lohmann V
  
• (2013). Tunable Substrates Unveil Chemical Complementation of a Genetic Cell Migration Defect. Adv Healthc Mater
  Hellmann JK, Perschmann N, Spatz JP, Frischknecht F
  
• (2014). A mechanistic framework for noncell autonomous stem cell induction in Arabidopsis. Proc Natl Acad Sci USA
  Daum G, Medzihradszky A, Suzaki T, Lohmann JU
  
• (2014). A TOGL domain specifically targets yeast CLASP to kinetochores to stabilize kinetochore microtubules. J Cell Biol
  Funk C, Schmeiser V, Ortiz J, Lechner J
  
• (2014). A vaccine targeting mutant IDH1 induces antitumour immunity. Nature
  Schumacher T, Bunse L, Pusch S, Sahm F, Wiestler B, Quandt J, Menn O, Osswald M, Oezen I, Ott M, Keil M, Balß J, Rauschenbach K, Grabowska AK, Vogler I, Diekmann J, Trautwein N, Eichmüller SB, ..., Wick W, Platten M
  
• (2014). Cyclosporin A inhibits Hepatitis B and Hepatitis D Virus entry by Cyclophilin-independent interference with the NTCP receptor. J Hepatol
  Nkongolo S, Ni Y, Lempp FA, Kaufman C, Lindner T, Esser-Nobis K, Lohmann V, Mier W, Mehrle S, Urban S
  
• (2014). Cytosolic peroxidases protect the lysosome of bloodstream african trypanosomes from ironmediated membrane damage. PLoS Pathog
  Hiller C, Nissen A, Benítez D, Comini MA, Krauth-Siegel RL
  
• (2014). E-CRISP: fast CRISPR target site identification. Nat Methods
  Heigwer F, Kerr G, Boutros M
  
• (2014). Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structurebased mechanistic dissection of a molecular motor. Acta Crystallogr D Biol Crystallogr
  Zeymer C, Barends TRM, Werbeck ND, Schlichting I, Reinstein J
  
• (2014). Male-female communication triggers calcium signatures during fertilization in Arabidopsis. Nat Commun
  Denninger P, Bleckmann A, Lausser A, Vogler F, Ott T, Ehrhardt DW, Frommer WB, Sprunck S, Dresselhaus T, Grossmann G
  
• (2014). RGS5 promotes arterial growth during arteriogenesis. EMBO Mol Med
  Arnold C, Feldner A, Pfisterer L, Hödebeck M, Troidl K, Genové G, Wieland T, Hecker M, Korff T
  
• (2014). RNA Specificity and Regulation of Catalysis in the Eukaryotic Polynucleotide Kinase Clp1. Mol Cell
  Dikfidan A, Loll B, Zeymer C, Magler I, Clausen T, Meinhart A
  
• (2014). Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1u. EMBO J
  Chen CY, Malchus NS, Hehn B, Stelzer W, Avci D, Langosch D, Lemberg MK
  
• (2014). Structure of the complete bacterial SRP Alu domain. Nucleic Acids Res
  Kempf G, Wild K, Sinning I
  
• (2014). The E3 Ligase CUL3/RDX Controls Centromere Maintenance by Ubiquitylating and Stabilizing CENP-A in a CAL1-Dependent Manner. Dev Cell
  Bade D, Pauleau AL, Wendler A, Erhardt S
  
• (2014). The Yeast ER- Intramembrane Protease Ypf1 Refines Nutrient Sensing by Regulating Transporter Abundance. Mol Cell
  Avci D, Fuchs S, Schrul B, Fukumori A, Breker M, Frumkin I, Chen CY, Biniossek ML, Kremmer E, Schilling O, Steiner H, Schuldiner M, Lemberg MK
  
• (2014). Translational Regulation of Specific mRNAs Controls Feedback Inhibition and Survival during Macrophage Activation. PLoS Genet
  Schott J, Reitter S, Philipp J, Haneke K, Schäfer H, Stoecklin G
  
• 2014). Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair. Genome Res
  Auer TO, Duroure K, De Cian A, Concordet JP, Del Bene F
  
• 2014). Quantitative determination of decitabine incorporation into DNA and its effect on mutation rates in human cancer cells. Nucleic Acids Res
  Öz S, Raddatz G, Rius M, Blagitko-Dorfs N, Lübbert M, Maercker C, Lyko F
  
• (2015). A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain. Cancer Cell
  Selvaraj D, Gangadharan V, Michalski CW, Kurejova M, Stösser S, Srivastava K, Schweizerhof M, Waltenberger J, Ferrara N, Heppenstall P, Shibuya M, Augustin HG, Kuner R
  
• (2015). Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys. Proc Natl Acad Sci USA,
  Mockenhaupt S, Grosse S, Rupp D, Bartenschlager R, Grimm D
  
• (2015). Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis. Nat Commun
  Linster E, Stephan I, Bienvenut WV, Maple-Grødem J, Myklebust LM, Huber M, Reichelt M, Sticht C, Geir Møller S, Meinnel T, Arnesen T, Giglione C, Hell R, Wirtz M
  
• (2015). Evidence that hepatitis B virus replication in mouse cells is limited by the lack of a host cell dependency factor. J Hepatol
  Lempp FA, Mutz P, Lipps C, Wirth D, Bartenschlager R, Urban S
  
• (2015). Identification and functional characterization of rare SHANK2 variants in schizophrenia. Mol Psychiatry
  Peykov S, Berkel S, Schoen M, Weiss K, Degenhardt F, Strohmaier J, Weiss B, Proepper C, Schratt G, Nöthen MM, Boeckers TM, Rietschel M, Rappold GA
  
• (2015). Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy. Autophagy
  Meissner C, Lorenz H, Hehn B, Lemberg MK
  
• (2015). Nanoscale control of surface immobilized BMP-2: toward a quantitative assessment of BMP-mediated signaling events. Nano Lett
  Schwab EH, Pohl TL, Haraszti T, Schwaerzer GK, Hiepen C, Spatz JP, Knaus P, Cavalcanti-Adam EA
  
• (2015). Operon structure and cotranslational subunit association direct protein assembly in bacteria. Science
  Shieh YW, Minguez P, Bork P, Auburger JJ, Guilbride DL, Kramer G, Bukau B
  
• (2015). Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut. Cell Rep
  Dutta D, Dobson AJ, Houtz PL, Gläßer C, Revah J, Korzelius J, Patel PH, Edgar BA, Buchon N
  
• (2015). Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling. Nat Commun
  Zuckermann M, Hovestadt V, Knobbe-Thomsen CB, Zapatka M, Northcott PA, Schramm K, Belic J, Jones DT, Tschida B, Moriarity B, Largaespada D, Roussel MF, Korshunov A, Reifenberger G, Pfister SM, Lichter P, Kawauchi D, Gronych J
  
• (2015). Sox2, Tlx, Gli3 and Her9 converge on Rx2 to define retinal stem cells in vivo. EMBO J
  Reinhardt R, Centanin L, Tavhelidse T, Inoue D, Wittbrodt B, Concordet JP, Martinez- Morales JR, Wittbrodt J
  
• (2015). Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold. J Cell Biol
  Gaik M, Flemming D, von Appen A, Kastritis P, Mücke N, Fischer J, Stelter P, Ori A, Bui KH, Baßler J, Barbar E, Beck M, Hurt E
  
• (2015). The inner workings of the hydrazine synthase multiprotein complex. Nature
  Dietl A, Ferousi C, Maalcke WJ, Menzel A, de Vries S, Keltjens JT, Jetten MS, Kartal B, Barends TR
  
• (2015). The serine protease inhibitor Serpin A3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase. Nat Med
  Vicuña L, Strochlic DE, Latremoliere A, Bali KK, Simonetti M, Husainie D, Prokosch S, Riva P, Griffin RS, Njoo C, Gehrig S, Mall MA, Arnold B, Devor M, Woolf CJ, Liberles SD, Costigan M, Kuner R
  
• (2015). Transcriptional refractoriness is dependent on core promoter architecture. Nat Commun
  Cesbron F, Oehler M, Ha N, Sancar G, Brunner M
  
• (2015). X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis. Nature
  Haslinger K, Peschke M, Brieke C, Maximowitsch E, Cryle MJ
  
• 2015). A Time-Calibrated Road Map of Brassicaceae Species Radiation and Evolutionary History. Plant Cell
  Hohmann N, Wolf EM, Lysak MA, Koch MA
  
• Compartment-specific aggregases direct distinct nuclear and cytoplasmic aggregate deposition. EMBO J
  Miller SB, Ho CT, Winkler J, Khokhrina M, Neuner A, Mohamed MY, Guilbride DL, Richter K, Lisby M, Schiebel E, Mogk A, Bukau B
  
• (2016). A FRET-based study reveals site-specific regulation of spindle position checkpoint proteins at yeast centrosomes. Elife
  Gryaznova Y, Koca Caydasi A, Malengo G, Sourjik V, Pereira G
  
• (2016). Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2. Mol Cell
  Sharma S, Poetz F, Bruer M, Ly-Hartig TBN, Schott J, Séraphin B, Stoecklin G
  
• (2016). Alternative splicing affects the subcellular localization of Drosha. Nucleic Acids Res
  Link S, Grund SE, Diederichs S
  
• (2016). Architecture of the 90S pre-ribosome: a structural view on the birth of the eukaryotic ribosome. Cell
  Kornprobst M, Turk M, Kellner N, Cheng J, Flemming D, Kos-Braun I, Kos M, Thoms M, Berninghausen O, Beckmann R, Hurt E
  
• (2016). Blue light-induced LOV domain dimerization enhances the affinity of Aureochrome 1a for its target DNA sequence. Elife
  Heintz U, Schlichting I
  
• (2016). Global profiling of SRP interaction with nascent polypeptides. Nature
  Schibich D, Gloge F, Pöhner I, Björkholm P, Wade RC, von Heijne G, Bukau B, Kramer G
  
• (2016). New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis. Angew Chem Int Ed Engl
  Kittilä T, Mollo A, Charkoudian LK, Cryle MJ
  
• (2016). Progress of endocytic CHRN to autophagic degradation is regulated by RAB5-GTPase and T145 phosphorylation of SH3GLB1 at mouse neuromuscular junctions in vivo. Autophagy
  Wild F, Khan MM, Straka T, Rudolf R
  
• (2016). Protein Abundance Control by Non-coding Antisense Transcription. Cell Rep
  Huber F, Bunina D, Gupta I, Khmelinskii A, Meurer M, Theer P, Steinmetz LM, Knop M
  
• (2016). Regulation of the P450 oxygenation cascade involved in glycopeptide antibiotic biosynthesis. J Am Chem Soc
  Peschke M, Haslinger K, Brieke C, Reinstein J, Cryle MJ
  
• (2016). Retinoic acid catabolizing enzyme CYP26C1 is a genetic modifier in SHOX deficiency. EMBO Mol Med
  Montalbano A, Juergensen L, Roeth R, Weiss B, Fukami M, Fricke-Otto S, Binder G, Ogata T, Decker E, Nuernberg G, Hassel D, Rappold GA
  
• (2016). Sensory input attenuation allows predictive sexual response in yeast. Nat Commun
  Banderas A, Koltai M, Anders A, Sourjik V
  
• (2016). Stimulated Emission Depletion Nanoscopy Reveals Time-Course of Human Immunodeficiency Virus Proteolytic Maturation. ACS Nano
  Hanne J, Göttfert F, Schimer J, Anders-Össwein M, Konvalinka J, Engelhardt J, Müller B, Hell SW, Kräusslich H-G
  
• (2016). Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction. Nucleic Acids Res
  Becker MM, Lapouge K, Segnitz B, Wild K, Sinning I
  
• (2016). Sugar Influx Sensing by the Phosphotransferase System of Escherichia coli. PLoS Biol
  Somavanshi R, Ghosh B, Sourjik V
  
• (2016). SuReSim: simulating localization microscopy experiments from ground truth models. Nat Methods
  Venkataramani V, Herrmannsdörfer F, Heilemann M, Kuner T
  
• (2016). TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus. Nucleic Acids Res
  Senis E, Mockenhaupt S, Rupp D, Bauer T, Paramasivam N, Knapp B, Gronych J, Grosse S, Windisch MP, Schmidt F, Theis FJ, Eils R, Lichter P, Schlesner M, Bartenschlager R, Grimm D
  
• (2016). The Crystal Structure of RosB: Insights into the Reaction Mechanism of the First Member of a Family of Flavodoxin-like Enzymes. Angew Chem Int Ed Engl
  Konjik V, Brünle S, Demmer U, Vanselow A, Sandhoff R, Ermler U, Mack M
  
• (2016). The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1- dependent nuclear export complexes. Nat Commun
  Ritterhoff T, Das H, Hofhaus G, Schröder RR, Flotho A, Melchior F
  
• (2016). Transient RNA-DNA Hybrids Are Required for Efficient Double- Strand Break Repair. Cell
  Ohle C, Tesorero R, Schermann G, Dobrev N, Sinning I, Fischer T
  
• (2017). Glutaredoxin catalysis requires two distinct glutathione interaction sites. Nat Commun
  Begas P, Liedgens L, Moseler A, Meyer AJ, Deponte M
  
• (2017). Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory. EMBO J
  Bröker-Lai J, Kollewe A, Schindeldecker B, Pohle J, Nguyen Chi V, Mathar I, Guzman R, Schwarz Y, Lai A, Weißgerber P, Schwegler H, Dietrich A, Both M, Sprengel R, Draguhn A, Köhr G, Fakler B, Flockerzi V, Bruns D, Freichel M
  
• (2017). Human phosphatase CDC14A regulates actin organization through dephosphorylation of epithelial protein lost in neoplasm. Proc Natl Acad Sci USA
  Chen NP, Uddin B, Hardt R, Ding W, Panic M, Lucibello I, Kammerer P, Ruppert T, Schiebel E
  
• (2017). Induction of Chromosome Instability by Activation of Yes Associated Protein and Forkhead box M1 in Liver Cancer. Gastroenterology
  Weiler SM, Pinna F, Wolf T, Lutz T, Geldiyev A, Sticht C, Knaub M, Thomann S, Bissinger M, Wan S, Rössler S, Becker D, Gretz N, Lang H, Bergmann F, Ustiyan V, Kalin TV, Singer S, Lee JS, Marquardt JU, Schirmacher P, Kalinichenko VV, Breuhahn K
  
• (2017). Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun
  Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti HH, Ermakova O, Rempel E, Stoeckli ET, Ruiz de Almodóvar C
  
• (2017). Neural stem cells induce the formation of their physical niche during organogenesis. Elife
  Seleit A, Krämer I, Riebesehl BF, Ambrosio EM, Stolper JS, Lischik CQ, Dross N, Centanin L
  
• (2017). Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siena Screening. Mol Cell
  Willemsen J, Wicht O, Wolanski JC, Baur N, Bastian S, Haas DA, Matula P, Knapp B, Meyniel-Schicklin L, Wang C, Bartenschlager R, Lohmann V, Rohr K, Erfle H, Kaderali L, Marcotrigiano J, Pichlmair A, Binder M
  
• (2017). Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding. Cell,
  Döring K, Ahmed N, Riemer T, Suresh HG, Vainshtein Y, Habich M, Riemer J, Mayer MP, O'Brien EP, Kramer G, Bukau B
  
• (2017). Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes. Nat Commun
  Schopp IM, Amaya Ramirez CC, Debeljak J, Kreibich E, Skribbe M, Wild K, Béthune J
  
• (2017). Strigolactone- and Karrikin-Independent SMXL Proteins Are Central Regulators of Phloem Formation. Curr Biol
  Wallner ES, López-Salmerón V, Belevich I, Poschet G, Jung I, Grünwald K, Sevilem I, Jokitalo E, Hell R, Helariutta Y, Agustí J, Lebovka I, Greb T
  
• (2017). Structural basis of HypK regulating N-terminal acetylation by the NatA complex. Nat Commun
  Weyer FA, Gumiero A, Lapouge K, Bange G, Kopp J, Sinning I
  
• (2017). Sulfur availability regulates plant growth via glucose-TOR signaling. Nat Commun
  Dong Y, Silbermann M, Speiser A, Forieri I, Linster E, Poschet G, Allboje Samami A, Wanatabe M, Sticht C, Teleman AA, Deragon JM, Saito K, Hell R, Wirtz M
  
• (2017). Telomere Length Determines TERRA and R-Loop Regulation through the Cell Cycle. Cell
  Graf M, Bonetti D, Lockhart A, Serhal K, Kellner V, Maicher A, Jolivet P, Teixeira MT, Luke B
  
• (2017). Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities. Nucleic Acids Res
  Bunina D, Štefl M, Huber F, Khmelinskii A, Meurer M, Barry JD, Kats I, Kirrmaier D, Huber W, Knop M
  
• (2018). BRI1 controls vascular cell fate in the Arabidopsis root through RLP44 and phytosulfokine signaling. Proc Natl Acad Sci USA
  Holzwart E, Huerta AI, Glöckner N, Garnelo Gómez B, Wanke F, Augustin S, Askani JC, Schürholz AK, Harter K, Wolf S
  
• (2018). Capsid protein structure, self-assembly, and processing reveal morphogenesis of the marine virophage mavirus. Proc Natl Acad Sci USA
  Born D, Reuter L, Mersdorf U, Mueller M, Fischer MG, Meinhart A, Reinstein J
  
• (2018). Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis. Nat Commun
  Bucher D, Frey F, Sochacki KA, Kummer S, Bergeest JP, Godinez WJ, Kräusslich HG, Rohr K, Taraska JW, Schwarz US, Boulant S
  
• (2018). Identification, Biosynthesis, and Decapping of NAD-Capped RNAs in B. subtilis. Cell Rep
  Frindert J, Zhang Y, Nübel G, Kahloon M, Kolmar L, Hotz-Wagenblatt A, Burhenne J, Haefeli WE, Jäschke A
  
• (2018). Mapping degradation signals and pathways in a eukaryotic N-terminome. Mol Cell
  Kats I, Khmelinskii A, Kschonsak M, Huber F, Knieß R, Bartosik A, Knop M
  
• (2018). Neurovascular Communication during CNS Development. Dev Cell
  Paredes I, Himmels P, Ruiz de Almodóvar C
  
• (2018). Phenotypic memory in Bacillus subtilis links dormancy entry and exit by a spore quantity-quality tradeoff. Nat Commun
  Mutlu A, Trauth S, Ziesack M, Nagler K, Bergeest JP, Rohr K, Becker N, Höfer T, Bischofs IB
  
• (2018). Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll Like Receptor 3 in Hepatocytes. Gastroenterology
  Grünvogel O, Colasanti O, Lee JY, Klöss V, Belouzard S, Reustle A, Esser-Nobis K, Hesebeck-Brinckmann J, Mutz P, Hoffmann K, Mehrabi A, Koschny R, Vondran FWR, Gotthardt D, Schnitzler P, Neumann-Haefelin C, Thimme R, Binder M, Bartenschlager R, Dubuisson J, Dalpke AH, Lohmann V
  
• (2018). SHRED Is a Regulatory Cascade that Reprograms Ubr1 Substrate Specificity for Enhanced Protein Quality Control during Stress. Mol Cell
  Szoradi T, Schaeff K, Garcia-Rivera EM, Itzhak DN, Schmidt RM, Bircham PW, Leiss K, Diaz-Miyar J, Chen VK, Muzzey D, Borner GHH, Schuck S
  
• (2018). Single event visualization of unconventional secretion of FGF2. J Cell Biol
  Dimou E, Cosentino K, Platonova E, Ros U, Sadeghi M, Kashyap P, Katsinelos T, Wegehingel S, Noé F, García-Sáez AJ, Ewers H, Nickel W
  
• (2018). The lncRNA CASC9 and RNA binding protein HNRNPL form a complex and coregulate genes linked to AKT signaling. Hepatology
  Klingenberg M, Groß M, Goyal A, Polycarpou-Schwarz M, Miersch T, Ernst AS, Leupold J, Patil N, Warnken U, Allgayer H, Longerich T, Schirmacher P, Boutros M, Diederichs S
  
• (2018). The ng_ζ1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis. Nat Commun
  Rocker A, Peschke M, Kittilä T, Sakson R, Brieke C, Meinhart A