Project Details
Projekt
Membrane-engineering as a tool to control the behavior of mesenchymal stem cells in biofabrication processes (B05)
Subject Area
Biomaterials
Term
since 2018
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 326998133
The interaction of cells with bioinks, as well as direct cell-cell interaction, is essential for biofabrication of tissue constructs. This project aims to reduce shear stress during bioprinting, to increase cell proliferation in the hydrogel, to influence cell-cell aggregation and spheroid formation, and to optimize cell-ink interaction by coupling a specific galectin-1 ligand via cell surface modification by membrane engineering. The long-term goal is to apply membrane engineering for cell and bioink modification to optimize the post-fabrication behavior of cells in biofabricated constructs.
DFG Programme
CRC/Transregios
Applicant Institution
Julius-Maximilians-Universität Würzburg
Project Heads
Professorin Dr. Regina Ebert; Professor Dr. Lutz Nuhn, since 7/2023; Professor Dr. Jürgen Seibel
