Reporter-conjugated bioinks for the investigation of cellular interactions in biofabrication (B06)

• Subject Area: Biomaterials ; Cell Biology
• Term: since 2018
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 326998133

The aim of B06 is the development of a modular reporter ink for biofabrication. The interactions between cells are to be systematically investigated in detail via integrated reporter functions in the bioink after the printing process. For this purpose, a reporter ink platform is to be developed that can be precisely printed, delivers stable 3D constructs and can be modified site-specifically in order to be able to functionally incorporate the reporters for cell adhesion and proteolytic degradation. In the long term, the reporter's ink should enable insights into biochemical and biomechanical processes during the maturation of cells in 3D constructs.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 225: From the fundamentals of biofabrication towards functional tissue models
• Applicant Institution: Julius-Maximilians-Universität Würzburg
• Project Heads: Dr.-Ing. Rainer Detsch; Privatdozentin Dr. Tessa Charlotte Lühmann, since 1/2022; Dr. Ingo Thievessen, until 12/2021