Asymmetric protein sorting via localizd translation - The role of ZBP protein in directing mRNA localization and translation

• Applicant: Professor Dr. Stefan Hüttelmaier
• Subject Area: Cell Biology
• Term: from 2007 to 2015
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 33442413

No abstract available

Publications

• (2009). Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs. Rna 15, 104-115
  Weidensdorfer, Doreen; Stöhr, Nadine; Baude, Anne; Lederer, Marcell; Köhn, Marcel; Schierhorn, Angelika; Buchmeier, Sabine; Wahle, Elmar & Hüttelmaier, Stefan
  
• (2012). IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling. Genes & development 26, 176-189
  Stohr, N., Kohn, M., Lederer, M., Glass, M., Reinke, C., Singer, R.H., and Huttelmaier, S.
  
• (2012). IGF2BP1: a post-transcriptional "driver" of tumor cell migration. Cell adhesion & migration 6, 312-318
  Stöhr, Nadine & Hüttelmaier, Stefan
  
• (2013). Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression? Cellular and molecular life sciences: CMLS 70, 2657-2675
  Bell, Jessica L.; Wächter, Kristin; Mühleck, Britta; Pazaitis, Nikolaos; Köhn, Marcel; Lederer, Marcell & Hüttelmaier, Stefan
  
• (2013). IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG). Nucleic acids research 41, 6618-6636
  Zirkel, Anne; Lederer, Marcell; Stöhr, Nadine; Pazaitis, Nikolaos & Hüttelmaier, Stefan
  
• (2013). Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA-binding proteins) is modulated by distinct RNA-binding domains. Biological chemistry 394, 1077-1090
  Wächter, Kristin; Köhn, Marcel; Stöhr, Nadine & Hüttelmaier, Stefan
  
• (2014). Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma. Hepatology 59, 1900-1911
  Gutschner, Tony; Hämmerle, Monika; Pazaitis, Nikolaos; Bley, Nadine; Fiskin, Evgenij; Uckelmann, Hannah; Heim, Andreas; Groβ, Matthias; Hofmann, Nina; Geffers, Robert; Skawran, Britta; Longerich, Thomas; Breuhahn, Kai; Schirmacher, Peter; Mühleck, Britta; Hüttelmaier, Stefan & Diederichs, Sven
  
• (2014). The role of the oncofetal IGF2 mRNA- binding protein 3 (IGF2BP3) in cancer. Seminars in cancer biology 29C, 3-12
  Lederer, Marcell; Bley, Nadine; Schleifer, Christian & Hüttelmaier, Stefan