Project Details
Projekt
Modulation of tyrosine receptor signaling investigated by NMR spectroscopy (P10)
Subject Area
Structural Biology
Term
since 2022
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 450648163
The central aim of project P10 is to investigate fundamental aspects of tyrosine kinase receptor signaling pathways for two pharmacological relevant receptors (FGFR and EPH) and their respective ligands. The dynamics of receptor/ligand interaction and the influence of inhibitors of low molecular weight will be investigated, using several biophysical and structural biology techniques, in particular NMR spectroscopy, available within CRC 1507.
DFG Programme
Collaborative Research Centres
Applicant Institution
Goethe-Universität Frankfurt am Main
Project Head
Professor Dr. Harald Schwalbe
