Metalloenzymes, Bioinspired Complexes and Hybrids for H2 Activation (B03)

• Subject Area: Physical Chemistry of Molecules, Liquids and Interfaces, Biophysical Chemistry ; Inorganic Molecular Chemistry - Synthesis and Characterisation
• Term: since 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 510228793

The project interrogates the role of non-covalent interactions and proton relays in the confined space of en-zyme active sites for H+/H2 interconversion by hydrogenases, as archetypal PCET enzymes. Natural, semi-synthetic, and model [Fe]- and [NiFe]-hydrogenases will be examined by para-H2 enhanced NMR spectroscopy to identify the essential moieties involved in H2 splitting and design efficient biomimetic catalysts that rely on functional groups in the second coordination sphere of active metal sites. B03 collaborates with A02 (NMR spectroscopy), A05 ((spectro)electrochemistry), B01 (theory), B02 (EPR spectroscopy), and Ö01 (public out-reach).

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1633: Pushing Electrons with Protons – Unifying Multi-Electron Redox Catalysis by Proton-Coupled Electron Transfer
• Applicant Institution: Georg-August-Universität Göttingen
• Project Heads: Dr. Stefan Glöggler; Professor Dr. Franc Meyer