Molecular analysis of viral mycotoxins in the yeasts Zygosaccaromyces and Hanseniaspora and characterization of their toxin-encoding dsRNA genomes

Applicant Professor Dr. Manfred Josef Schmitt

Subject Area Microbial Ecology and Applied Microbiology

Term from 2002 to 2008

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 5382255

Final Report Year 2007

Final Report Abstract

No abstract available

(2002). The Zygosaccharomyces bailii antifungal virus toxin zygocin: cloning and expression in a heterologous fungal host. Mol. Microbiol. 46: 1095-1105
Weiler F, Rehfeldt K, Bautz F, Schmitt MJ
(2003). Transfection of yeast with toxin-coding dsRNA viruses of Zygosaccharomyces bailii and toxin purification by receptor-mediated affinity chromatography. In: Wolf, K., Breunig, K., Barth, E. (eds.). Lab Manunual on Non- Conventional Yeasts: Biochemistry, Molecular Biology, and Biotechnology. Springer- Verlag, pp. 417-425
Weiler, F., M.J. Schmitt
(2003). Zygocin, a secreted antifungal toxin of the yeast Zygosaccharomyces bailii and its effect on sensitive fungal cells. FEMS Yeast Res. 3: 69-76
Weiler F, Schmitt MJ
(2005). Viral killer toxins induce caspasemediated apoptosis in yeast. J. Cell Biol. 168: 353-358
Reiter J, Hecker E, Madeo F, Schmitt MJ
(2005). Zygocin - a monomeric protein toxin secreted by virusinfected Zygosaccharomyces bailii. In: Schmitt, M.J., Schaffrath, R. (eds.). Microbial Protein Toxins. Top. Curr. Genet. 11: 175-187
Weiler, F., M.J. Schmitt
(2006). Yeast viral killer toxins: lethality and self-protection. Nat. Rev. Microbiol. 4: 212-221
Schmitt MJ, Breinig F
(2007). Nützliche Proteine mit furchterregendem Namen: Killertoxine aus Hefen. Biol. Unserer Zeit 2: 104-111
Breinig F, Schmitt MJ