SFB 1748:  Principles of Reproduction – Unravelling the Molecular Mechanisms of Male Infertility

• Subject Area: Medicine ; Biology
• Term: since 2026
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 549467913

No abstract available

• DFG Programme: Collaborative Research Centres

Current projects

• A01 - Epigenetic mechanisms in the physiological development and malignant transformation of primordial germ cells (Project Head Kerl, Kornelius )
• A02 - Biochemical properties of the seminiferous tubule extracellular matrix (Project Heads Eble, Johannes Andreas ;  Schlatt, Stefan )
• A03 - Functional genetics in male congenital malformations (Project Heads Busch, Ph.D., Alexander S. ;  Ziller, Michael J. )
• A04 - Testis channelopathies (Project Heads Seebohm, Guiscard ;  Spehr, Marc )
• A05 - Spatial sensing of spermatogonial stem cells: cues for cell (dys)function (Project Heads Neuhaus, Nina ;  Wickström, Sara A. )
• A06 - Characterisation of the zygotene cilium in human spermatogenesis (Project Heads Friedrich, Corinna ;  Wallmeier, Julia )
• A07 - The genomic landscape of non-obstructive azoospermia (Project Head Tüttelmann, Frank )
• B01 - Sperm flagella dysfunction related to defects of inner dynein arms and associated structures (Project Head Raidt, Johanna )
• B02 - Deciphering the role of adenylate kinases and microtubule inner proteins in male fertility (Project Head Omran, Heymut )
• B03 - Molecular mechanisms of calcium signalling in human sperm (Project Heads Brenker, Christoph ;  Strünker, Timo )
• B04 - In situ structural analysis of the human CatSper-channel complex (Project Head Gatsogiannis, Christos )
• B05 - The role of the MHC for fertilisation and infertility from a fish perspective (Project Heads Kurtz, Joachim ;  Peuß, Robert )
• B06 - Epigenetic regulation of early embryonic development (Project Head Bedzhov, Ivan )
• INF - Research data infrastructure for multi-modal analyses (Project Heads Heider, Dominik ;  Storck, Michael ;  Vogl, Raimund )
• RTG - Integrated Research Training Group (RTG.MS) ‘Reproduction.MS training centre in translational science’ (Project Heads Neuhaus, Nina ;  Strünker, Timo )
• SCWIKO - Science Communication (Project Heads Beumer, Cristin ;  Schieb, Carla )
• Z01 - Central coordination (Project Head Tüttelmann, Frank )
• Z02 - Science-clinics interface (Project Heads Kliesch, Sabine ;  Omran, Heymut ;  Risse, Benjamin ;  Schubert, Maria )
• Z03 - GenOMICs (Project Heads Heider, Dominik ;  Stoll, Monika ;  Tüttelmann, Frank )

• Applicant Institution: Universität Münster
• Participating University: Rheinisch-Westfälische Technische Hochschule Aachen; Institut für Biologie II (Zoologie)
• Participating Institution: Max-Planck-Institut für molekulare Biomedizin; Zell- und Gewebedynamik
• Spokesperson: Professor Dr. Frank Tüttelmann