TRR 63:  Integrated Chemical Processes in Liquid Multiphase Systems

• Subject Area: Thermal Engineering/Process Engineering ; Chemistry ; Computer Science, Systems and Electrical Engineering
• Term: from 2010 to 2022
• Website: Homepage
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 56091768

The project focusses on methods which are required for the development of homogeneously catalyzed pocesses in liquid multiphase systems. The first pillar of the research program are novel phase systems: thermomorphic (TMS) and micellar (MLS) solvent systems as well as Pickering emulsions (PE). In spite of the great interest of chemical industry, these innovative phase systems are still being used to a small extent. On the one hand, there is a lack of necessary chemical-physical fundamentals as well as of process-oriented principles. On the other hand, the proof that economically and environmentally attractive overall processes can be realized with these phase systems is still missing. Therefore, as a second pillar, the methodological gaps for the design of efficient processes are closed by an integrated research approach in order to create the prerequisites for efficient chemical production processes based on liquid, reactive, mul-tiphase systems.The third pillar is the homogeneously catalyzed refining of long-chain olefins as well as unsaturated oleo compounds as typical representatives of biobased raw materials. In the third funding period, the project has two main objectives:1. Deepening and broadening of the chemical-physical and process engineering principles of homogeneously catalyzed processes with several liquid phases. 2. Further development, integration and application as well as validation of the methods for fast, systematic model-based process development by means of two challenging new reaction systems, the reductive amination and the hydroaminomethylation. The projects dealing with the coordination of the model-based process development, the validation of the processes in miniplants and the development, control and testing of the process operation are summarized in a new project area D. In close collaboration with almost all other projects, these new processes are to be developed within four years from initial laboratory experiments for catalyst and phase system selection, to the demonstration of controlled operation in miniplants. As a summary of the developments and achievements in the project a system for the selection of appropriate phase systems for a broad spectrum of homogeneously catalyzed reactions is devel-oped. Moreover a general methodology for fast model-based process development in close interac-tion of experiment, modeling and optimization is developed.

• DFG Programme: CRC/Transregios
• International Connection: United Kingdom

Completed projects

• A01 - Transition metal catalysed hydroformylation and hydroesterification of petro- and oleochemical starting materials with temperature controlled catalyst separation in gas/liquid/liquid systems (Project Heads Behr, Arno ;  Vorholt, Andreas )
• A02 - Investigations of homogeneously catalzyed reactions in micellar solvent systems (Project Head Schomäcker, Reinhard )
• A03 - Kinetics of reductive amination and hydroaminomethylation in reactive multiphase fluid systems (Project Heads Hamel, Christof ;  Seidel-Morgenstern, Andreas )
• A04 - Choice of solvents for selective control of kinetics and thermodynamics of chemical reactions (Project Heads Sadowski, Gabriele ;  Stein, Matthias )
• A05 - Measurement of Phase Equilibria of Surfactant Containing Systems (Project Head Enders, Sabine )
• A06 - Mass transfer and interfacial phenomena in micellar three phase systems and pickering emulsions (Project Head Kraume, Matthias )
• A08 - Thermodynamics of Crystallization and Adsorption of Linear and Branched Molecules (Project Heads Enders, Sabine ;  Zeiner, Tim )
• A09 - Solubilization of weakly polar compounds in micellar systems (Project Heads Enders, Sabine ;  Sadowski, Gabriele )
• A10 - Gas/liquid mass transfer in reactive multiphase systems (Project Heads Böhm, Lutz ;  Hecht, Kristin ;  Kraume, Matthias )
• A11 - Homogeneously catalyzed reductive amination of long-chain aldehydes and hydroaminomethylation of long-chain alkenes with integrated catalyst separation in thermos-regulated solvent systems (Project Heads Seidensticker, Thomas ;  Vogt, Dieter )
• B01 - Optimal reactor design and operation for liquid multiphase systems (Project Heads Sundmacher, Kai ;  Zähringer, Katharina )
• B02 - Ultrafiltration of micellar systems in integrated processes (Project Heads Drews, Anja ;  Kraume, Matthias )
• B03 - Hybrid separation processes for purification of wide and close boiling mixtures in hydroformylation of long chained olefins (Project Heads Górak, Andrzej ;  Kreis, Peter ;  Rüther, Feelly )
• B04 - Hydroformylation of petrochemical- and oleochemical starting materials in micellar solvent systems in a continuously operated miniplant with a highly efficient catalyst recycling (Project Heads Barz, Tilman ;  Repke, Jens-Uwe ;  Schomäcker, Reinhard )
• B05 - Hydroformylation and hydroesterification of petrochemicals and oleochemicals in thermo-morphic solvent systems in a continuously operated miniplant with highly efficient catalyst recycling (Project Heads Behr, Arno ;  Górak, Andrzej ;  Lutze, Philip ;  Vogt, Dieter )
• B06 - Design of Pickering emulsions for the separation of products with different polarity (Project Heads Drews, Anja ;  von Klitzing, Regine )
• B08 - Characterization, modeling and simulation of phase separation in micellar multiphase systems (Project Heads Kraume, Matthias ;  Thévenin, Dominique )
• B09 - Integrated design of thermomorphic multicomponent systems (TMS) and separation processes for the efficient recovery of homogeneous catalysts and solvents (Project Heads Kienle, Achim ;  Sundmacher, Kai )
• C01 - Model-based management of the development of novel chemical production processes (Project Head Engell, Sebastian )
• C02 - Hierarchical Simulation of Integrated Chemical Processes (Project Heads Arellano-Garcia, Harvey ;  Wozny, Günter )
• C03 - Global optimisation of integrated liquid multiphase systems (Project Heads Kienle, Achim ;  Michaels, Dennis )
• C04 - Process operation and control of the miniplants (Project Heads Barz, Tilman ;  Engell, Sebastian ;  Repke, Jens-Uwe )
• D01 - Fast model-based design of chemical processes with several liquid phases (Project Heads Engell, Sebastian ;  Sadowski, Gabriele ;  Sundmacher, Kai )
• D02 - Demonstration of the fast track process development and of the optimal operation of the reductive amination of long-chained aldehydes in emulsion systems (Project Head Repke, Jens-Uwe )
• D03 - Development and testing of integrated reaction and catalyst separation for the homogeneously cata-lyzed reductive amination and hydraminomethylation of long-chain alkenes in a miniplant (Project Heads Skiborowski, Mirko ;  Vogt, Dieter )
• D04 - Control and optimal operation of the reductive amination and of the hydroaminomethylation in the demonstration plants (Project Heads Engell, Sebastian ;  Esche, Erik )
• T02 - Hybrid separation processes: modeling and design of membrane-assisted distillation (Project Head Górak, Andrzej )
• Z01 - Central Tasks (Project Head Kraume, Matthias )

• Applicant Institution: Technische Universität Berlin
• Co-Applicant Institution: Otto-von-Guericke-Universität Magdeburg; Technische Universität Dortmund
• Participating University: Hochschule Anhalt; Hochschule für Technik und Wirtschaft Berlin; Karlsruher Institut für Technologie; Technische Universität Darmstadt
• Participating Institution: Max-Planck-Institut für Dynamik komplexer technischer Systeme
• Spokesperson: Professor Dr.-Ing. Matthias Kraume