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Energy optimization as an organizing principle for protein dynamics at the synapse (C11*)

Subject Area Molecular Biology and Physiology of Neurons and Glial Cells
Term since 2026
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 317475864
 
Our prior modelling work suggests that protein dynamics inside neurons can be described using coupled diffusion equations capturing parameters such as protein translation from mRNAs, lateral diffusion, degradation, uptake into spines, and others. In this project, we will study how synapses organize their energy budget for all of these parameters, and study what strategies the pre- and post-synapse use to minimize their energy budgets, while maintaining function.
DFG Programme Collaborative Research Centres
Applicant Institution Georg-August-Universität Göttingen
 
 

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