Project Details
Projekt
NMR investigations of retinal binding proteins (P13)
Subject Area
Structural Biology
Term
from 2008 to 2020
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 57566863
Our research interest focuses on investigating light-induced conformational changes and dynamics of light sensitive retinal-binding membrane proteins by light-triggered, time-resolved NMR spectroscopy. In the last funding period of CRC 807, combined research efforts in solution and solid-state NMR spectroscopy together with optical spectroscopy revealed the structural and dynamic properties of channelrhodopsin, which is the key tool in optogenetics. Furthermore, we investigated the dynamics of photoactivated bovine rhodopsin with its subsequent desensitization by arrestin.
DFG Programme
Collaborative Research Centres
Applicant Institution
Goethe-Universität Frankfurt am Main
Project Head
Professor Dr. Harald Schwalbe
