Klinikum der Universität München
Campus Großhadern
Medizinische Klinik und Poliklinik III
Address
Marchioninistraße 15
81377 München
Deutschland
GERiT
This institution in GERiT
81377 München
Projects
Research Grants
Current projects
Aberrant Cathepsin S (CTSS) Activity in Follicular Lymphoma
(Applicant
Weigert, Oliver
)
Co-Evolution of Follicular Lymphoma and its Microenvironment during Disease Formation, Progression and Development of Treatment Resistance
(Applicants
Schmidt-Supprian, Marc
;
Weigert, Oliver
)
Dissecting intratumoral inflammation during evolution of drug tolerance in lung cancer
(Applicant
Sos, Martin
)
Completed projects
Characterization of antigen presentation and processing in CD40-activated B cells and its influence on the induction of CD4 and CD8 T cells responses
(Applicant
Schultze, Joachim L.
)
Characterization of tumor-infiltrating B-cells in cutaneous T-cell lymphoma
(Applicants
von Bergwelt-Baildon, Michael
;
Theurich, Sebastian
)
Ein Chemical-Genomics Ansatz für die Identifizierung von Onkogenabhängigkeit beim kleinzelligen Bronchialkarzinom
(Applicant
Thomas, Roman
)
Ethische, rechtliche und klinische Rahmenbedingungen passiver Sterbehilfe und Sterbebegleitung. Von der Problem- und Bedarfsanalyse zur Intervention und Evaluation
(Applicant
Hiddemann, Wolfgang
)
Mechanismen der Transformation hämatopoetischer Zellen durch AML-spezifische Mutationen der Rezeptortyrosinkinase FLT3 in vitro und in vivo
(Applicant
Spiekermann, Karsten
)
Regulation der Signaltransduktion von Zytokinrezeptoren bei der akuten myeloischen Leukämie
(Applicant
Spiekermann, Karsten
)
Rolle des physiologischen Microenviroment im Knochenmark in der Pathogenese der akuten myeloischen Leukämie
(Applicant
Fiegl, Michael
)
Collaborative Research Centres
Current projects
Targeted exploitation of inflammatory programs in SCLC
(Project Head
Sos, Martin
)
Completed projects
Aberrant Cathepsin S (CTSS) Activity in Follicular Lymphoma
(Project Head
Weigert, Oliver
)
Central Administration
(Project Heads
Bohlander, Stefan Klaus
;
Hiddemann, Wolfgang
)
Clonal evolution of high risk acute myeloid leukemia
(Project Head
Spiekermann, Karsten
)
Contribution of somatic mutations in hematopoietic stem / progenitor cells to oncogenic evolution in follicular lymphoma
(Project Head
Weigert, Oliver
)
Evolution of transcription factor mutations in myeloid leukemias
(Project Heads
Greif, Philipp
;
Hiddemann, Wolfgang
)
Hitze-Schock-Proteine (HSP) als immunmodulatorische Mediatoren für dendritische Zellen: Zytokinfunktion und Antigenpräsentation
(Project Heads
Issels, Rolf D.
;
Nößner, Elfriede
)
Mechanisms of leukemic transformation by the receptor tyrosine kinase FLT3 in vitro and in vivo
(Project Head
Spiekermann, Karsten
)
MYC gene family members as modulators of tumorigenesis and druggable signaling pathways in SCLC
(Project Head
Sos, Martin
)
Rekombinante Hitzeschockproteine (HSP) 70 als immunmodulatorische Mediatoren im "Cross-Talk" von dendritischen Zellen mit T-Zellen und NKZellen
(Project Heads
Issels, Rolf D.
;
Nößner, Elfriede
)
SFB 684: Molecular Mechnisms of Normal and Malignant Hematopoiesis
(Spokespersons
Bohlander, Stefan Klaus
;
Hiddemann, Wolfgang
)
Research Fellowships
Completed projects
Etablierung und Charakterisierung eines Tiermodells für die inflammatorisch bedingte Kanzerogenese im Pankreas
(Applicant
Westphalen, Christoph Benedikt
)
Identifikation neuer Onkogene mit funktioneller Relevanz für die Pathogenese peripherer T-Zell Lymphome
(Applicant
Weigert, Oliver
)
Simultane Aktivierung und Inhibition antiapoptotischer Signaltransduktionswege in der Akuten Myeloischen Leukämie
(Applicant
Fiegl, Michael
)
The role of available hematopoietic stem cell niches during leukemic and pre-leukemic engraftment
(Applicant
Köhnke, Thomas
)
WBP Fellowship
Current projects
The CAR T-cell epigenome: Decipher and reprogramme fate decisions of CAR T-cell dysfunction
(Applicant
Blumenberg, Viktoria
)
Priority Programmes
Completed projects
The role of TET proteins in myeloid neoplasia
(Applicants
Bohlander, Stefan Klaus
;
Leonhardt, Heinrich
;
Spiekermann, Karsten
)
Clinical Trials
Current projects
Post-resection therapy in patients with metastatic colorectal Cancer (PORT) AIO KRK01418
(Applicant
Modest, Dominik
)
CRC/Transregios
Current projects
Metabolic reprogramming to optimize the cellular fitness and function of engineered T cells
(Project Heads
Theurich, Sebastian
;
Väth, Ph.D., Martin
)
Research Training Groups
Current projects
GRK 2338: Targets in Toxicology - Deciphering Therapeutic Targets in Lung Toxicology
(Spokesperson
Gudermann, Thomas
)
