Universitätsklinikum Düsseldorf
Institut für Biochemie und Molekularbiologie II
Address
Universitätsstraße 1
40225 Düsseldorf
Deutschland
GERiT
This institution in GERiT
40225 Düsseldorf
Projects
Research Grants
Current projects
Impact of IL-6 signaling on hepatic thrombopoietin production, platelet turnover and platelet activation upon acute inflammation (thrombo-inflammation)
(Applicant
Elvers, Margitta
)
Modularity and application of synthetic cytokine receptors
(Applicant
Scheller, Jürgen
)
Specificity and functional modulation of RHOGDIs: An in vitro reconstitution approach
(Applicant
Ahmadian, Reza
)
Use of synthetic cytokine receptors against viral infection and cancer
(Applicants
Scheller, Jürgen
;
Xu, Haifeng
)
Completed projects
ADAM protease activationin the context of IL-6R biology
(Applicant
Scheller, Jürgen
)
Biochemical investigations on the Rho-protein family and their interacting partner
(Applicant
Ahmadian, Reza
)
Kontrollmechanismen von GTPasen der Rho-Familie
(Applicant
Ahmadian, Reza
)
Membrane sorting and membrane-associated protein complexes in interleukin 6 receptor signaling
(Applicant
Scheller, Jürgen
)
Molecular Principles of Interleukin-6/-11 Classic and Trans-Signalling
(Applicant
Scheller, Jürgen
)
The role of the Interleukin-6 receptor in liver damage and regeneration
(Applicant
Scheller, Jürgen
)
Collaborative Research Centres
Completed projects
Di-protein-dependent cardiovascular homeostasis
(Project Head
Piekorz, Roland
)
Mechanisms of ADAM 17 activation in the context of IL-6R biology
(Project Head
Scheller, Jürgen
)
Mechanisms of hepatic stellate cell differentiation in liver
(Project Head
Ahmadian, Reza
)
Mitotic spindle apparatus and nuclear pore complexes: Role in environmentally induced cellular aging
(Project Head
Piekorz, Roland
)
Pro- und anti-inflammatory effects of interleukins in cardiac ischemia: Function of interleukin-23, interleukin-27 und -35
(Project Heads
Flögel, Ulrich
;
Scheller, Jürgen
)
Role of soluble interleukin-6 receptor in liver damage and regeneration
(Project Head
Scheller, Jürgen
)
The CD73-adenosine-Interleukin 6-type cytokines axis in myocardial infarction
(Project Heads
Friebe, Daniela
;
Scheller, Jürgen
;
Schrader, Jürgen
)
The soluble IL6R: Generation and physiological relevance
(Project Heads
Rose-John, Stefan
;
Scheller, Jürgen
)
International Research Training Groups
Completed projects
GRK 1902: Intra- and Interorgan Communication of the Cardiovascular System
(Spokesperson
Gödecke, Axel
)
Research Training Groups
Completed projects
GRK 2576: vivid - in vivo investigations towards the early development of type 2 diabetes
(Spokesperson
Al-Hasani, Hadi
)