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TRON - Translationale Onkologie
an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz

Address Freiligrathstraße 12
55131 Mainz
Deutschland

GERiT This institution in GERiT

55131 Mainz

Projects

Research Grants
- Current projects
  - CAncer REsistance to T cell mediated immunotherapy – Dissection of the intercellular CONNECTivity mechanisms to overcome therapeutic resistance (CARE CONNECT)
    (Applicant Stanganello, Eliana )
  - Synthesizing regenerative potential and preventing cancer risk by spatio-temporal control of cellular plasticity.
    (Applicant Kim, Johnny )
- Completed projects
  - Fostering antigen spread and dissecting tumor evolution in response to neoantigen-specific cancer vaccination
    (Applicant Diken, Mustafa )
WBP Position
- Current projects
  - Deciphering gene regulatory networks driving aging and rejuvenation in the human endothelium at single-cell resolution
    (Applicant Lüttmann, Felipe Francisco )
  - Development of regulatory T cells expressing specific chimeric antigen receptors directed towards citrullinated peptides
    (Applicant Özdemir, Ph.D., Alper Tunga )
Collaborative Research Centres
- Current projects
  - Integrated OMICS, Bioinformatics and Morpho-molecular Immunomonitoring Unit
    (Project Heads Albrecht, Christian ; Bukur, Valesca ; Gaida, Matthias ; Tenzer, Stefan )
  - Neo-epitope specific CD4+ T cells – Anti-tumoral mechanisms and their modulation
    (Project Heads Kreiter, Sebastian ; Sahin, Ugur )
  - SFB 1399: Mechanisms of drug sensitivity and resistance in small cell lung cancer
    (Spokesperson Thomas, Roman )
- Completed projects
  - Evaluation of systemic mRNA/peptide-based nanoparticle vaccines in melanoma tumor models
    (Project Heads Diken, Mustafa ; Schild, Hansjörg )
  - Targeting of cancer-associated fibroblasts with drug-loaded polymeric nanoparticles to improve im-mune therapy for primary and secondary liver tumors
    (Project Heads Diken, Mustafa ; Kaps, Leonard ; Lammers, Twan )

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