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Project Details

Institution

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Universitätsklinikum Halle (Saale) AöR
Universitätsklinik und Poliklinik für Innere Medizin IV
Professur für Molekulare Krebstherapie

Address Ernst-Grube-Straße 40
06120 Halle
Deutschland

GERiT This institution in GERiT

06120 Halle

Projects

Independent Junior Research Groups
- Completed projects
  - Der Hedgehog Signalweg als therapeutisches Target in leukämischen Stammzellen bei der Akuten Myeloischen Leukämie
    (Applicant Dierks, Christine )
Research Units
- Current projects
  - FOR 2033: The Hematopoietic Niches
    (Spokesperson Oostendorp, Robert A.J. )
  - FOR 2674: Aging-related epigenetic remodeling in acute myeloid leukemia
    (Spokesperson Lübbert, Ph.D., Michael )
  - FOR 5659: TARGET-MPN: TARgetinG disease pErsisTence and progression of MyeloProliferative Neoplasms (MPN)
    (Spokesperson Heidel, Florian )
  - Identification of niche factors and inflammatory cytokines driving clonal progression in MPN
    (Applicant Dierks, Christine )
- Completed projects
  - Dissecting molecular basis and cellular heterogeneity of slow progressing 'smoldering' AMLs of the elderly
    (Applicants Dierks, Christine ; Trumpp, Ph.D., Andreas )
  - Dissecting the interaction of the PIM1/CXCR4 axis and Hedgehog signaling within the niche determing HSC mobilization and leukemic transformation
    (Applicants Dierks, Christine ; Duyster, Justus )
Collaborative Research Centres
- Completed projects
  - Role of the Hedgehog Signaling Mediators Smo and STK36 (Fused) in Metastasis and Cancer Stem Cell Maintenance of Solid Tumors
    (Project Head Dierks, Christine )

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