SPP 1109:  Embryonal and Tissue-Specific Stem Cells - Regenerative Systems for Cell and Tissue Repair

• Subject Area: Medicine
• Term: from 2001 to 2008
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5470870

No abstract available

• DFG Programme: Priority Programmes
• International Connection: USA

Projects

• Analysis of the growth- and differentiation potential of conditioned, adult hepatocytes versus hepatic precursor cells as an effective means of repopulation of the liver in the rat model (Applicant König, Sarah )
• Characterization of immunologic properties of murine and human embryonic stem cells and embryonic stem cell-derived cardiomyocytes (Applicant Saric, Tomo )
• Coordinator application within the Priority Program "Stem cells" (SPP 1109) (Applicant Wobus, Anna M. )
• Derivation and transplantation of neural precursors from human embryonic stem cells (Applicant Brüstle, Oliver )
• Developmental potentials of murine neural stem cells (Applicant Müller, Albrecht M. )
• Differentiation of mouse embryonic stem (ES) cells into pancreatic precursor and insulin-producing ß-cells (Applicant Wobus, Anna M. )
• Enrichment and isolation of in vitro differentiated ES cell derived cardiomyocytes and cardiac precursor cells for transplantation into the infarcted myocardium (Applicant Franz, Wolfgang-M. )
• Functional analysis of Notch1 in the maintenance and differentiation of adult mamammalian neural stem cells. (Applicant Taylor, Ph.D., Verdon )
• Functional characterisation of putative pluripotency controlling genes and their roles in establishing transcriptional networks and signalling pathways crucial to stem cell biology (Applicant Adjaye, James )
• Genes and proteins determining the phenotype of mammary epithelial stern cells (Applicant Groner, Bernd )
• Genetic determinants of adult neurogenesis from neural stem cells in the hippocampus (Applicant Kempermann, Gerd )
• Glial cells make neurons: molecular mechanisms of neurogenesis (Applicant Götz, Magdalena )
• Glial cells make neurons: molecular mechanisms of neurogenesis (Applicant Schachner, Melitta )
• Identification of the most reprogramming-potent oocyte for more efficient cloning and for a long-term approach to the isolation of reprogramming factor(s) (Applicant Hiiragi, Takashi )
• In vitro differentiation, transplantation and functional analysis of ES cell-derived cardiac precursors (Applicant Fleischmann, Bernd )
• In vitro transdifferentiation of human endothelial progenitor cells into cardiac myocytes: determination of the underlying mechanisms (Applicant Dimmeler, Stefanie )
• Induktion von Pluripotenz: Rolle Raf- und Myc-abhängiger Signalwege bei der Retro-/Trans-Differenzierung neuraler Zellen (Applicant Rapp, Ulf Rüdiger )
• Mechanisms of asymmetric cell division of human stem and progenitor cells (Applicant Giebel, Bernd )
• Molecular analysis of gene expression in hematopoietic and neural stem cells, and functional analysis of stem cell genes. (Applicant Zenke, Martin )
• Molecular detection of stem cell plasticity (Applicant von Kalle, Christof )
• Molecular mechanisms involved in the maintenance of the undifferentiated state in human embryonic stem cells (Applicant Besser, Ph.D., Daniel )
• Molecular mechanisms of lineage decisions mediated by Notch signalling in adult and embryonic hematopoietic development (Applicant Just, Ursula )
• Neurale Stammzellen des adulten Gehirns: Transdifferenzierung und Rekrutierung ependymaler und endothelialer Zellen (Applicant Plate, Karlheinz )
• Peripheral neural stem cells - maintenance in peripheral ganglia and nerves (Applicant Rohrer, Hermann )
• Plasticity Potential and Asymmetric Divisions of Hematopoietic Stem Cells (Applicant Ho, Anthony D. )
• Prominin-1-GFP knock-in mouse line: A novel source of fluorescent stem cells to monitor the history of the transplanted murine hematopoietic stem cells (Applicant Corbeil, Denis )
• Reprogramming mechanisms of bone marrow-derived hepatocytes (Applicant Willenbring, Holger )
• Selection and manipulation of mesenchymal stem cells for the generation of myoblasts and cardiomyocytes (Applicant Braun, Thomas )
• Stem cells in Caenorhabditis elegans (Applicant Schnabel, Ralf )
• Stem Cells to Germ Cells: Development of Germ Stem Cell Systems to Study Gametogenesis and Meiosis (Applicant Jessberger, Rolf )
• Targeting of hematopoietic stem cells to the CNS and differentiation into glia and neurons (Applicant Neumann, Harald )
• Tenascin-C and neural stem cell differentiation (Applicant von Holst, Alexander )
• The cellular and molecular analysis of amphibian spinal cord regeneration, and the comparison with mammalian cells (Applicant Tanaka, Ph.D., Elly Margaret )
• The metabolic characteristics of stem cells (Applicant Cross, Michael )
• The metabolic characteristics of stem cells (Applicant Cross, Michael )
• The role of cell cycle length and interkinetic nuclear migration for the switch of neuroepithelial stem cells from symmetric proliferative to asymmetric neurogenic divisions (Applicant Huttner, Wieland B. )
• The role of the gene bazooka during asymmetric division of neuronal stem cells in Drosophila (Applicant Wodarz, Andreas )
• The role of the gene bozooka during asymmetric division of neural stem cells in Drosophila (Applicant Wodarz, Andreas )
• Zell- und molekularbiologische Analyse von De- und Redifferenzierungsvorgängen in porcinen und bovinen Kardiomyozyten in einem homologen und heterologen Kerntransfermodell (Applicant Niemann, Heiner )
• Zur Rolle der Mitochondrien bei der nukleären Reprogrammierung: Charakterisierung und funktionelle Analyse des Mitochondrien-assoziierten Epitopes PG-2 (Applicant Viebahn, Christoph )

• Spokesperson: Professorin Dr. Anna M. Wobus