SPP 1109:  Embryonale und gewebespezifische Stammzellen: Regenerative Zellsysteme für einen Zell- und Gewebeersatz

• Fachliche Zuordnung: Medizin
• Förderung: Förderung von 2001 bis 2008
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 5470870

Keine Zusammenfassung vorhanden

• DFG-Verfahren: Schwerpunktprogramme
• Internationaler Bezug: USA

Projekte

• Analysis of the growth- and differentiation potential of conditioned, adult hepatocytes versus hepatic precursor cells as an effective means of repopulation of the liver in the rat model (Antragstellerin König, Sarah )
• Cellular and molecular basis of neural stem cells converting to mesodermal derivatives during tail regeneration in Ambystoma mexicanum (Antragstellerin Tanaka, Ph.D., Elly Margaret )
• Characterization of immunologic properties of murine and human embryonic stem cells and embryonic stem cell-derived cardiomyocytes (Antragsteller Saric, Tomo )
• Coordinator Support (SPP 1109) Embryonic and somatic stem cells: Regenerative systems for cell and tissue repair (Antragstellerin Wobus, Anna M. )
• Derivation and transplantation of neural precursors from human embryonic stem cells (Antragsteller Brüstle, Oliver )
• Die molekulare Detektion von Stammzellplastizität (Antragsteller von Kalle, Christof )
• Enhancing the developmental potential of neural stem cells by epigenetic modification (Antragsteller Müller, Albrecht M. )
• Enrichment and isolation of in vitro differentiated ES cell derived cardiomyocytes and cardiac precursor cells for transplantation into the infarcted myocardium (Antragsteller Franz, Wolfgang-M. )
• Functional analysis of Notch1 in the maintenance and differentiation of adult mamammalian neural stem cells. (Antragsteller Taylor, Ph.D., Verdon )
• Functional characterisation of putative pluripotency controlling genes and their roles in establishing transcriptional networks and signalling pathways crucial to stem cell biology (Antragsteller Adjaye, James )
• Gene expression, commitment and differentiation of hematopoietic stem cells (Antragsteller Zenke, Martin )
• Genes and proteins determining the phenotype of mammary epithelial stern cells (Antragsteller Groner, Bernd )
• Genetic determinants of adult neurogenesis form neural stem cells in the hippocampus: role of Cdk5 (Antragsteller Kempermann, Gerd )
• Glial cells make neurons: molecular mechanisms of neurogenesis (Antragstellerin Götz, Magdalena )
• Glial cells make neurons: molecular mechanisms of neurogenesis (Antragstellerin Schachner, Melitta )
• Hematopoietic Stem Cells and Membrane Lipid Microdomains (Antragsteller Corbeil, Denis )
• Identification of the most reprogramming-potent oocyte for more efficient cloning and for a long-term approach to the isolation of reprogramming factor(s) (Antragsteller Hiiragi, Takashi )
• In vitro differentiation, transplantation and functional analysis of ES cell-derived cardiac precursors (Antragsteller Fleischmann, Bernd )
• In vitro transdifferentiation of human endothelial progenitor cells into cardiac myocytes: determination of the underlying mechanisms (Antragstellerin Dimmeler, Stefanie )
• Induktion von Pluripotenz: Rolle Raf- und Myc-abhängiger Signalwege bei der Retro-/Trans-Differenzierung neuraler Zellen (Antragsteller Rapp, Ulf Rüdiger )
• Mechanisms of asymmetric cell division of human stem and progenitor cells (Antragsteller Giebel, Bernd )
• Molecular mechanisms involved in the maintenance of the undifferentiated state in human embryonic stem cells (Antragsteller Besser, Ph.D., Daniel )
• Molekulare Mechanismen Notch vermittelter Zelllinienentscheidungen bei der entwicklung hämatopoetischer Zellen aus adulten und embryonalen Stammzellen (Antragstellerin Just, Ursula )
• Mouse embryonic stem (ES) cells and somatic stem/progenitor cells for the generation of pancreatic precursor and insulin-producing cells (Antragstellerin Wobus, Anna M. )
• Neurale Stammzellen des adulten Gehirns: Transdifferenzierung und Rekrutierung ependymaler und endothelialer Zellen (Antragsteller Plate, Karlheinz )
• Peripheral neural stem cells - maintenance in peripheral ganglia and nerves (Antragsteller Rohrer, Hermann )
• Plasticity Potential and Asymmetric Divisions of Hematopoietic Stem Cells (Antragsteller Ho, Anthony D. )
• Reprogramming mechanisms of bone marrow-derived hepatocytes (Antragsteller Willenbring, Holger )
• Selection and manipulation of mesenchymal stem cells for the generation of myoblasts and cardiomyocytes (Antragsteller Braun, Thomas )
• Stem cells in Caenorhabditis elegans (Antragsteller Schnabel, Ralf )
• Stem Cells to Germ Cells: Development of Germ Stem Cell Systems to Study Gametogenesis and Meiosis (Antragsteller Jessberger, Rolf )
• Targeting of hematopoietic stem cells to the CNS and differentiation into glia and neurons (Antragsteller Neumann, Harald )
• Tenascin-C and neural stem cell differentiation (Antragsteller von Holst, Alexander )
• The metabolic characteristics of stem cells (Antragsteller Cross, Michael )
• The metabolic characteristics of stem cells (Antragsteller Cross, Michael )
• The role of cell cycle length and interkinetic nuclear migration for the switch of neuroepithelial stem cells from symmetric proliferative to asymmetric neurogenic divisions (Antragsteller Huttner, Wieland B. )
• The role of the gene bazooka during asymmetric division of neuronal stem cells in Drosophila (Antragsteller Wodarz, Andreas )
• The role of the gene bozooka during asymmetric division of neural stem cells in Drosophila (Antragsteller Wodarz, Andreas )
• Zell- und molekularbiologische Analyse von De- und Redifferenzierungsvorgängen in porcinen und bovinen Kardiomyozyten in einem homologen und heterologen Kerntransfermodell (Antragsteller Niemann, Heiner )
• Zur Rolle der Mitochondrien bei der nukleären Reprogrammierung: Charakterisierung und funktionelle Analyse des Mitochondrien-assoziierten Epitopes PG-2 (Antragsteller Viebahn, Christoph )

• Sprecherin: Professorin Dr. Anna M. Wobus