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Institution
Humboldt-Universität zu Berlin
Institut für Biologie
Arbeitsgruppe Experimentelle Biophysik
Address
Invalidenstraße 42
10115 Berlin
Deutschland
GERiT
This institution in GERiT
10115 Berlin
Projects
Research Grants
Current projects
Neorhodopsins, Near-infrared sensing Rhodopsin-cyclases
(Applicants
Bartl, Franz
;
Broser, Matthias
)
Physical constraints to tune B-cell activation and differentiation
(Applicant
Klotzsch, Enrico
)
Completed projects
Der Photochromismus des Channelrhodopsin-1 aus Volvox carteri (VCHR)
(Applicants
Elstner, Marcus
;
Hegemann, Peter
)
Functional in vivo Studies of Algal Sensory Photoreceptors
(Applicant
Hegemann, Peter
)
Investigation of BLUF photochemistry by isotopic labeling of flavin cofactor and amino acid side chains
(Applicant
Hegemann, Peter
)
Optogenetic dissection of cyclic nucleotide signaling in a model parasite Toxoplasma gondii
(Applicant
Gupta, Nishith
)
Probing functional connectivity in vivo via holographic and molecular targeting
(Applicant
Hegemann, Peter
)
The Channelrhodopsin mechanism
(Applicant
Hegemann, Peter
)
Ultrafast dynamics of biomolecules studied by vibrational spectroscopy on selectively isotope labeled proteins
(Applicant
Hegemann, Peter
)
Research Units
Completed projects
Biochemical and spectroscopic characterization of blue light receptors with LOV and BLUF-domain-type chromophores from microalgae and purple bacteria
(Applicants
Hegemann, Peter
;
Schlichting, Ilme
)
Biochemical and spectroscopic characterization of three blue light receptors with LOV and BLUF-domain-type chromophores
(Applicant
Schlichting, Ilme
)
Central Coordination Project
(Applicant
Hegemann, Peter
)
Central Project
(Applicants
Hegemann, Peter
;
Mittag, Maria
)
Central Project
(Applicants
Hegemann, Peter
;
Mittag, Maria
;
Weber, Andreas P.M.
)
Channelrhodopsin colour tuning
(Applicants
Elstner, Marcus
;
Hegemann, Peter
)
Characterization of biomodal light-switchable rhodopsins and tailoring for optogentic application
(Applicant
Hegemann, Peter
)
FOR 526: Blue-light Sensitive Photoreceptors
(Spokesperson
Hegemann, Peter
)
FOR 1279: Protein-based Photoswitches as Optogenetic Tools
(Spokesperson
Hegemann, Peter
)
Functional characterization of novel rhodopsins of Chlamydomonas and other algae
(Applicant
Hegemann, Peter
)
Molecular mechanisms of gene silencing and positional effects in Green Algae
(Applicant
Hegemann, Peter
)
Nuclear gene targeting in Chlamydomonas reinhardtii
(Applicant
Hegemann, Peter
)
Zentralprojekt
(Applicant
Hegemann, Peter
)
Collaborative Research Centres
Current projects
Development of molecular tools for manipulating and studying memory engrams
(Project Heads
Hegemann, Peter
;
Rosenmund, Christian
;
Rost, Benjamin
;
Schmitz, Dietmar
;
Vierock, Johannes
)
Completed projects
Expression and spectroscopic characterization of channelrhodopsins and enzymerhodopsins from Chlamydomonas reinhardtii
(Project Head
Hegemann, Peter
)
Gating and ion transport dynamics in channelrhodopsins and light-driven pumps
(Project Heads
Budisa, Nediljko
;
Hegemann, Peter
)
Proton exchange processes in phytochromes and retinal proteins investigated by MAS NMR
(Project Heads
Hegemann, Peter
;
Oschkinat, Hartmut
)
Rhodopsinregulierte ionale Signalprozesse in Chlamydomonas und Volvox
(Project Head
Hegemann, Peter
)
Sensorische Rhodopsine einzelliger Algen
(Project Head
Hegemann, Peter
)
Major Research Instrumentation
Completed projects
FTIR Spektrometer mit Laseranregungssystem
Priority Programmes
Completed projects
Cognitive performance as result of coordinated neuronal activity within developing prefrontal-hippocampal circuits
(Applicants
Denker, Michael
;
Hanganu-Opatz, Ileana L.
;
Hegemann, Peter
;
Oertner, Thomas
)
Development and Application of New Optogenetic Tools Targeted to Intracellular Compartments
(Applicants
Hegemann, Peter
;
Rost, Benjamin
)
Development and application of RoCK, a novel Rhodopsin Cyclase/ K+ channel-based optogenetic tool for silencing of excitable cells
(Applicants
Baier, Herwig
;
Hegemann, Peter
;
Schneider-Warme, Franziska
;
Seifert, Ph.D., Reinhard
)
Engineering of Chrimson for Subcellular Optogenetic application
(Applicants
Elstner, Marcus
;
Hegemann, Peter
;
Rost, Benjamin
)
Optogenetic dissection of the developing prefrontal-hippocampal circuitry that gates mnemonic and executive maturation
(Applicants
Denker, Michael
;
Hanganu-Opatz, Ileana L.
;
Hegemann, Peter
;
Oertner, Thomas
)
Shrimp Rhodopsins as new far-red absorbing optogenetic tools
(Applicant
Hegemann, Peter
)
CRC/Transregios
Completed projects
Optical control of calcium switches that orchestrate fast signaling in the brain.
(Project Heads
Hegemann, Peter
;
Plested, Andrew
)
Major Instrumentation Initiatives
Completed projects
A modular dual 2-photon microscope for multimodal optogenetics, synapse biophysics and beyond
Lattice Light Sheet Microscope (LLSM)
Clusters of Excellence
Completed projects
EXC 314: Unifying Concepts in Catalysis
(Spokesperson
Drieß, Matthias
)
Clusters of Excellence (ExStra)
Current projects
EXC 2049: NeuroCure – Comprehensive approaches to neurological and psychiatric disorders – from mechanisms to interventions –
(Spokespersons
Kühn, Andrea
;
Schmitz, Dietmar
)
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