Project Details

Professor Dr. Martin Zacharias

Address Technische Universität München (TUM)
Physik Department
Lehrstuhl für Theoretische Biophysik - Molekulardynamik
Ernst-Otto-Fischer-Straße 8
85748 Garching

Projects

As Applicant
- Current projects
  - Investigation of Protein-DNA recognition using Molecular Dynamics and advanced sampling simulations (Research Grants)
  - Mechanism of substrate processing of γ-secretase and influence by modulators studied using Molecular Dynamics simulations (Research Grants)
- Completed projects
  - Konformationsanalyse von nicht-kanonischen Strukturmotiven in RNA (Research Grants)
  - Untersuchung der SH2-Phosphotyrosinpeptid-Wechselwirkung und der Assoziation membranständiger a-Helices aus Signalübertragungsproteinen durch Computersimulation (Research Grants)
  - Strukturbildung und -veränderung durch Bindung von Peptiden und Proteinen an Ribonukleinsäuren (Research Grants)
  - Flexible protein-protein-docking: Development of new scoring functions and application to biologically important protein-protein interactions - Flexibles Protein-Protein-Docking (Research Grants)
  - Stability and dynamics of DNA molecules in solution and near material surfaces (Research Grants)
  - Enhancement of peptide binding to MHC class I molecules by small compounds - a combined biochemical and computational investigation (Research Grants)
  - Flexible Docking of Protein-Nucleic Acid Complexes (Research Grants)
  - Dynamics of Substrate-Protease Interactions (Research Units)
As Leader
- Completed projects
  - Compute Cluster (Major Research Instrumentation)
  - Compute-Clustr (Major Research Instrumentation)
As Project Head
- Completed projects
  - Computersimulation der Bindung von Liganden an SH2-Domänen (Collaborative Research Centres)
  - Simulation of nucleic acid dynamics and deformability during protein binding and damage recognition (Collaborative Research Centres)
  - Molecular Driving Forces for Global Changes in Proteins and Nucleic Acids (Collaborative Research Centres)
  - Association-induced conformational switching in biomolecules studied by Molecular Dynamics simulations (Collaborative Research Centres)
As Co-Investigator
- Current projects
  - The causes of MHC-I-opathies in cellular stress (Research Grants)

Servicenavigation

Hauptnavigation

Professor Dr. Martin Zacharias

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Martin Zacharias

Additional Information

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