Project Details

Professor Dr. Holger Gohlke

Address Heinrich-Heine-Universität Düsseldorf
Institut für Pharmazeutische und Medizinische Chemie
Universitätsstraße 1
40225 Düsseldorf

Projects

As Applicant
- Current projects
  - Disinhibition and inhibition of HCN2 channel function by ligand binding to the cyclic nucleotide binding domain (Research Units)
  - Chitin oligosaccharide recognition by human chitinase-like proteins: Deciphering CodeChi at the atomistic level and its impact on cellular signaling (Priority Programmes)
- Completed projects
  - Function of lipase-specific foldase for folding and secretion of a lipase from Pseudomonas aeruginosa (Research Grants)
  - Targeting spectrin redox switches to regulate the mechanoproperties of red blood cells. (Priority Programmes)
  - Targeting protein-protein interactions within the autophagy-inducing ULK1 complex for cancer therapy (Research Grants)
As Spokesperson
- Current projects
  - GRK 2158: Natural products and natural product analogs against therapy-resistant tumors and microorganisms: new lead structures and modes of action (Research Training Groups)
As Project Head
- Current projects
  - Functional state modulation of membrane proteins by dynamic association and dissociation (Collaborative Research Centres)
  - Acquisition – Processing – Sharing – Storage: Research data management for interdisciplinary membrane research (Collaborative Research Centres)
- Completed projects
  - Structural models and conformational dynamics of the G protein coupled bile acid receptor TGR5 (Collaborative Research Centres)
  - Integriertes Graduiertenkolleg (Collaborative Research Centres)
As Cooperation Partner
- Completed projects
  - Development of class IIa selective histone deacetylase inhibitors with chemosensitizing properties as anticancer agents (Research Grants)

Servicenavigation

Hauptnavigation

Professor Dr. Holger Gohlke

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Holger Gohlke

Additional Information

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