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Privatdozent Dr. Björn Buchholz

Address Universitätsklinikum Erlangen AöR
Medizinische Klinik 4 - Nephrologie und Hypertensiologie
Ulmenweg 18
91054 Erlangen

Projects

As Applicant
- Completed projects
  - The relevance of the hypoxia-inducible transcription factor HIF-1alpha for cyst growth in polycystic kidney disease (Research Grants)
  - Modulation of cyst growth in renal tissue from patients with autosomal dominant polycystic kidney disease in a human tissue-based 3D-in-vivo-model (Research Grants)
As Project Head
- Current projects
  - The impact of ROS, ferroptosis, glucose transport and IL-1 receptor signaling on the progression of ADPKD (CRC/Transregios)
  - 3D-in-ovo-model to study and modulate the growth of human renal cystic tissue and mouse kidney slices (CRC/Transregios)
- Completed projects
  - Slowing polycystic kidney disease by inhibition of HIF-1α-dependent- and calcium-mediated secretory signaling pathways (Collaborative Research Centres)
  - Fibronectin and its role in polycystic kidney diseases (Collaborative Research Centres)
As Cooperation Partner
- Completed projects
  - Regulation of calcium concentration in microdomains and primary cilium by TMEM16 proteins and role of TMEM16 and CFTR for renal cystogenesis (Research Grants)

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