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Professor Dr. Christian Michael Grimm

Address Ludwig-Maximilians-Universität München
Walther-Straub-Institut für Pharmakologie und Toxikologie
Nussbaumstraße 26
80336 München

Projects

As Applicant
- Current projects
  - Endolysosomal cation channels as novel targets for cancer therapy (Research Grants)
  - Role of two-pore channels in the astroglial Mechanosensitivity controlling water balance (Research Grants)
  - Deciphering new components of Ca2+-signaling in endolysosomes (Research Grants)
- Completed projects
  - Investigation of the role of TRPML channel family and two-pore channel family members in intracellular fusion processes and the cation homeostasis of endolysosomal vesicles (Research Grants)
  - Mechanisms of activation of lysosomal two-pore channel TPC2, a potential novel target for the treatment of lysosomal storage disorders and neurodegenerative diseases (Research Grants)
As Participating Researcher
- Current projects
  - GRK 2338: Targets in Toxicology - Deciphering Therapeutic Targets in Lung Toxicology (Research Training Groups)
As Project Head
- Current projects
  - Adenine nucleotide signaling in Ca2+-dependent mast cell activation: role of endolysosomal and plasmalemmal channels (Collaborative Research Centres)
  - Endolysosomal cation channels in synucleo- and tauopathies (CRC/Transregios)

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