SFB 1270:  ELectrically Active ImplaNts - ELAINE

• Subject Area: Computer Science, Systems and Electrical Engineering ; Biology ; Chemistry ; Mechanical and Industrial Engineering ; Materials Science and Engineering ; Mathematics ; Medicine ; Physics
• Term: since 2017
• Website: Homepage
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 299150580

No abstract available

• DFG Programme: Collaborative Research Centres
• International Connection: Italy

Current projects

• A02 - Refined multiscale and multiphysics models of electrical stimulation towards clinical applications (Project Heads Adrian, Simon ;  Appali, Revathi ;  van Rienen, Ursula ;  Schmidt, Christian ;  Zimmermann, Julius )
• A03 - Electrostimulation-induced cellular responses: Biomarkers for eustress levels and model implant surfaces (Project Heads Nebe, J. Barbara ;  Rebl, Henrike ;  Speller, Sylvia )
• A04 - Cell dynamics and cell mechanics on electrically conductive multilayers (Project Heads Delcea, Mihaela ;  Helm, Christiane A. )
• A06 - Mathematical modelling and data-driven multiscale analysis (Project Head Starke, Jens )
• A07 - Image-based modelling of angiogenesis and tissue remodelling for electrically active implants (Project Head Zeller-Plumhoff, Berit )
• B01 - Electrically conductive and piezoelectric materials for multifunctional implants for bone and cartilage regeneration (Project Heads Boccaccini, Aldo ;  Seitz, Hermann )
• B02 - Sensory and therapeutic functions for an energy-autonomous total hip replacement (Project Head Klüß, Daniel )
• B03 - Modelling and design of ultra-low power implants for closed-loop stimulation (Project Heads Haubelt, Christian ;  Hohlfeld, Dennis ;  Niemann, Christoph ;  Timmermann, Dirk )
• B06 - Efficient signal processing algorithms and architectures for in situ monitoring using electrically active implants and their closed-loop control (Project Heads Reichenbach, Marc ;  Spors, Sascha )
• B07 - Numerical methods for the prediction of physiological bone and cartilage properties (Project Head Adrian, Simon )
• C01 - Electro-physical stimulation of osseoinduction via alloplastic osteosynthesis system after ablative surgery in the mandible (Project Heads Dau, Michael ;  Engel, Nadja ;  Kämmerer, Peer )
• C02 - Electrical stimulation of articular cartilage: Evaluation of its potential for the repair of osteochondral defects in situ (Project Heads Bader, Rainer ;  Jonitz-Heincke, Anika ;  Seitz, Hermann )
• C03 - Deep brain stimulation in dystonia models: Biological implementation, definition of optimal stimulation parameters, and analysis of mechanisms (Project Heads Köhling, Rüdiger ;  Richter, Angelika ;  Richter Assencio, Franziska )
• C04 - Accelerometer-controlled adaptive deep brain stimulation in rat models of Parkinson’s disease to influence motor and non-motor behaviour (Project Heads Fauser, Mareike ;  Storch, Alexander )
• C05 - Translating advanced biophysical modelling into the clinical practice of deep brain stimulation programming (Project Head Horn, Ph.D., Andreas )
• INF - Information infrastructure (Project Heads Adrian, Simon ;  Krüger, Frank ;  van Rienen, Ursula ;  Sander, Manuela ;  Spors, Sascha )
• IRTG - Integrated Research Training Group (Project Heads Rebl, Henrike ;  Spors, Sascha ;  Storch, Alexander ;  Uhrmacher, Adelinde )
• S01 - Improving metrology and instrumentation of electrostimulation experiments (Project Heads Franz, Denise ;  Haubelt, Christian ;  van Rienen, Ursula ;  Spors, Sascha )
• Z - Central administrative tasks (Project Heads van Rienen, Ursula ;  Spors, Sascha )

Completed projects

• A01 - Computational models for analysing the impact of electric fields on intracellular and intercellular processes at different spatio-temporal scales (Project Head Uhrmacher, Adelinde )
• A05 - Dielectric evaluation of cellular and interfacial characteristics for electrical stimulation (Project Head Kolb, Jürgen )
• B05 - Assessment of the mechanical reliability of electrically active, porous and functionally graded implant structures by local damage approach (Project Head Sander, Manuela )

• Applicant Institution: Universität Rostock
• Participating University: Friedrich-Alexander-Universität Erlangen-Nürnberg; Hochschule Wismar; University of Applied Sciences; Technology, Business and Design; Johannes Gutenberg-Universität Mainz; Stiftung Tierärztliche Hochschule Hannover; Universität Greifswald; Universität zu Köln
• Spokespersons: Professorin Dr. Ursula van Rienen, until 12/2025; Professor Dr.-Ing. Sascha Spors, since 1/2026