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Institution

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Klinikum der Universität München
Campus Großhadern
Institut für Schlaganfall- und Demenzforschung (ISD)

Address Feodor-Lynen-Straße 17
81377 München
Deutschland

GERiT This institution in GERiT

81377 München

Projects

Research Fellowships
- Completed projects
  - Freisetzung mitochondrialer Proteine nach fokaler zerebraler Ischämie
    (Applicant Plesnila, Nikolaus )
Research Grants
- Current projects
- Completed projects
Clinical Research Units
- Completed projects
Independent Junior Research Groups
- Current projects
  - Deciphering the Role of Oligodendrocytes in the Pathogenesis of Alzheimer’s Disease
    (Applicant Jaekel, Sarah )
  - Multi-omic characterization of the immune mechanisms driving human atheroprogression
    (Applicant Georgakis, Ph.D., Marios )
- Completed projects
  - Brain-released alarmins as mediators of immunological comorbidities after stroke
    (Applicant Liesz, Arthur )
WBP Position
- Current projects
  - Serial Metabolomic Profiling to Inform on Novel Mechanisms and Biomarkers for Stroke
    (Applicant Vlegels, Naomi )
  - The long-term consequences of stroke on systemic immunity
    (Applicant Simats, Ph.D., Alba )
Research Units
- Current projects
  - Chronic inflammasome activation in post-stroke recovery
    (Applicants Hornung, Veit ; Liesz, Arthur ; Schmidt-Pogoda, Antje )
  - Coordination Funds
    (Applicant Liesz, Arthur )
  - FOR 2879: ImmunoStroke: From immune cells to stroke recovery
    (Spokesperson Liesz, Arthur )
  - Mechanisms of microglia-induced circuit remodeling in post-stroke recovery
    (Applicants Liesz, Arthur ; Magnus, Tim ; Misgeld, Thomas )
  - Meningeal immune cell priming for stroke recovery
    (Applicants Benakis, Corinne ; Meyer zu Hörste, Gerd ; Minnerup, Jens )
  - Microglia-PET as a surrogate marker for post-stroke neuroinflammation
    (Applicants Brendel, Matthias ; Dichgans, Martin ; Ziegler, Sibylle Ilse )
  - Standardization of animal models and outcome parameters
    (Applicants Langhauser, Friederike ; Llovera, Gemma )
- Completed projects
  - Strukturelle und funktionelle Charakterisierung der MIF/Chemokinrezeptor-Achse bei Atherosklerose und Myokardinfarkt
    (Applicant Bernhagen, Jürgen )
Collaborative Research Centres
- Current projects
  - Differential mechanisms of MIF proteins in atherosclerosis and selective peptide-based strategies for intervention
    (Project Heads Bernhagen, Jürgen ; Kapurniotu, Aphrodite )
  - Inflammation begets inflammation – impact of remote injuries on atherosclerosis progression
    (Project Heads Liesz, Arthur ; Sager, Hendrik )
  - Interactions of chemokines with heterologous effectors in atherosclerosis
    (Project Heads Bernhagen, Jürgen ; Gabius, Hans-Joachim ; von Hundelshausen, Philipp ; Koenen, Ph.D., Rory R. )
  - Mechanisms underlying the role of HDAC9 in atherosclerosis
    (Project Heads Asare, Yaw ; Dichgans, Martin ; Haffner, Christof )
- Completed projects
  - CXCR and CD74 receptor mechanisms of the cytokine MIF and their role in nephrotoxic nephritis
    (Project Heads Bernhagen, Jürgen ; Ostendorf, Tammo ; Weber, Christian )
  - Functional Analysis and bichemical Characterization of the mutant notch3 Receptor; Generation of a transgenic Mouse Model für Cadasil
    (Project Head Dichgans, Martin )
Major Research Instrumentation
- Completed projects
CRC/Transregios
- Current projects
  - Disease-overarching mechanisms of Treg-CNS interaction
    (Project Heads Bittner, Stefan ; Liesz, Arthur )
  - Microbiota-induced intestinal Treg cells modulate neuroinflammation
    (Project Heads Benakis, Corinne ; Regen, Tommy )
  - Molecular checkpoints regulating the repair capacity of surviving oligodendrocytes in an inflammatory environment
    (Project Heads Jaekel, Sarah ; Kerschensteiner, Martin )
  - Multicellular interactions of microglia in the chronically inflamed brain after ischemic stroke
    (Project Head Liesz, Arthur )
- Completed projects
  - Targeting MIF family proteins in liver fibrosis: Mechanisms and translational approaches
    (Project Heads Bernhagen, Jürgen ; Berres, Marie-Luise )
WBP Fellowship
- Completed projects
  - Elucidating the etiology of cryptogenic stroke with human genetics
    (Applicant Georgakis, Ph.D., Marios )
Priority Programmes
- Current projects
  - T cells as modulators of microglial reactivity in Alzheimer’s disease
    (Applicants Liesz, Arthur ; Tahirovic, Ph.D., Sabina )
International Research Training Groups
- Completed projects
  - GRK 1508: Arterial Remodelling
    (Spokesperson Bernhagen, Jürgen )
Clusters of Excellence
- Completed projects
  - EXC 1010: Munich Cluster for Systems Neurology (SyNergy)
    (Spokesperson Haass, Christian )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2145: Munich Cluster for Systems Neurology (SyNergy)
    (Spokespersons Haass, Christian ; Misgeld, Thomas )

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