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Institution
Johannes Gutenberg-Universität Mainz
Universitätsmedizin
Institut für Physiologische Chemie
Address
55099 Mainz
Deutschland
GERiT
This institution in GERiT
55099 Mainz
Projects
Research Fellowships
Completed projects
Suche nach Interaktionspartnern von neuronalen Intermediärfilamenten, den Neurofilament-Proteinen
(Applicant
Clement, Albrecht
)
Priority Programmes
Completed projects
Biomineralization in siliceous sponges: Isolation, cDNA sequencing, expression and characterization of the SiO2-synthesizing and degrading enzymes
(Applicant
Schröder, Heinz C.
)
Elucidation of phylogenetic processes during early evolution of basal Metazoa through the phylogenetic study of both, selected molecular marker genes and EST data
(Applicant
Wiens, Matthias P.
)
Genetically controlled self-assembly of inorganic-bioorganic hybrid structures: From sponge genes to layered functional materials
(Applicant
Wiens, Matthias P.
)
Hierarchical Architecture of Sponge Spicules: Bio-inspired assembly of multifunctional structures by biocatalytically active and structure-guiding proteins
(Applicants
Schröder, Heinz C.
;
Tremel, Wolfgang
)
Integrated Proteomics and Lipidomics Platform
(Applicants
Bindila, Ph.D., Laura
;
Distler, Ute
)
Protective mechanisms in nicotine-induced conditioned place preference and in vivo functional validation of candidate genes using rAAV
(Applicant
Lutz, Beat
)
Research Units
Completed projects
Characterization of cell type-specific endocannabinoid signaling at biochemical and behavioral level
(Applicant
Lutz, Beat
)
Common resources of the research unit
(Applicant
Zimmer, Andreas
)
Detection and quantification of endocannabinoids by LC-MS/MS
(Applicant
Lutz, Beat
)
FOR 926: Physiology and Pathophysiology of the Endocannabinoid System
(Spokespersons
Lutz, Beat
;
Zimmer, Andreas
)
Research Grants
Current projects
CellREADR-mediated BDNF overexpression in serotonergic neurons as therapeutic approach to promote stress resilience
(Applicant
Leschik, Julia
)
Completed projects
Cell-type specific signalling of the CB1 cannabinoid receptor
(Applicant
Monory, Krisztina
)
Corticotropin releasing hormone (CRH) in neuroprotection: molecular and cellular analysis of the neurotrophic acitivities of a stress-related neuropeptide
(Applicant
Behl, Christian
)
Failure in PP2A/mTOR signaling, local protein synthesis and its consequences on functional connectivity in neurons from patients with Opitz BBB/G syndrome
(Applicants
Berninger, Benedikt
;
Schweiger, Susann
)
Generierung und Charakterisierung einer knock-in Maus, die BDNF-YFP unter Kontrolle der endogenen regulatorischen Elemente des BDNF-Gens exprimiert
(Applicants
Leßmann, Volkmar
;
Lutz, Beat
)
Kombinatorische Synthese und biologische Evaluierung von Modulatoren der Proteinkinase C
(Applicant
Waldmann, Herbert
)
Molecular genetic investigations on the physiological role of the Cannabinoid receptor CB 1 in the central nervous system of the mouse
(Applicant
Lutz, Beat
)
Collaborative Research Centres
Completed projects
Central coordination
(Project Head
Lutz, Beat
)
Charakterisierung von Proteinen und Peptiden - Peptidsynthese (Teil A); zentrale Syntheseleistungen für den SFB (Teil B)
(Project Head
Kellner, Roland
)
Development and refinement of mouse models for studying stress resilience
(Project Heads
Lutz, Beat
;
Müller, Marianne
)
Endocannabinoids in negative feedback mechanisms: involvement of epigenetic mechanisms underlying homeostasis and the shift to allostasis
(Project Head
Lutz, Beat
)
Lipid signaling by anandamide and the bliss of resilience: genetic models at cellular and neural-network levels
(Project Heads
Luhmann, Heiko J.
;
Lutz, Beat
)
Post-transcriptional mechanisms in synaptic plasticity and memory consolidation: Role of mRNA stability
(Project Heads
Lutz, Beat
;
Niehrs, Ph.D., Christof
)
SFB 1193: Neurobiology of Resilience to stress-related mental dysfunction: from understanding mechanisms to promoting prevention
(Spokesperson
Lutz, Beat
)
Stabilization of neuronal protein homeostasis by adaptation of chaperone activity to longterm proteotoxic stress in vivo
(Project Heads
Behl, Christian
;
Clement, Albrecht
)
The role of the protein receptor-mediated endocytosis 8 (RME8) in neuronal homeostasis
(Project Heads
Behl, Christian
;
Clement, Albrecht
)
Unraveling the relation between adult-born hippocampal neurons’ circuit activity and resilience
(Project Heads
Berninger, Benedikt
;
Leschik, Julia
)
Major Research Instrumentation
Completed projects
Flüssigkeitschromatographie- Triplequadrupol-Massenspektroskop (LC-MS/MS)
Light-sheet microscope
CRC/Transregios
Completed projects
Cell type-specificity of endocannabinoid signaling in amygdala-BNST projections regulating sustained fear
(Project Heads
Lutz, Beat
;
Pape, Hans-Christian
)
Science Communication, Research Data, eResearch
Completed projects
Open Access Publishing 2016 - 2017 / Mainz University and Mainz University Medical Center
(Applicant
Hofmeister, Wolfgang
)
Research Training Groups
Completed projects
GRK 1044: Developmental and Disease-induced Modifications of the Nervous System
(Spokesperson
Luhmann, Heiko J.
)
International Research Training Groups
Completed projects
GRK 1549: Molecular and Cellular Glyco-Sciences (MCGS). Understanding Structure/Function Relationships of Carbohydrate/Protein Interactions
(Spokesperson
Moerschbacher, Bruno
)
Additional Information
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