Universitätsmedizin Göttingen
Zentrum Physiologie und Pathophysiologie
Institut für Herz- und Kreislaufphysiologie
Address
Humboldtallee 23
37073 Göttingen
Deutschland
GERiT
This institution in GERiT
37073 Göttingen
Projects
Research Grants
Current projects
Nanodomains of ROS production control cardiomyocyte metabolism and contractility
(Applicants
Brandenburg, Sören
;
Katschinski, Dörthe M.
)
Redox control of ER-mitochondria communication: Implications for melanoma pathobiology
(Applicants
Bogeski, Ivan
;
Simeth-Crespi, Nadja Anita
)
Towards optogenetic laryngeal pacemaking - first proof-of-concept study in pigs
(Applicants
Beutner, Dirk
;
Brügmann, Tobias
;
Ruther, Patrick
)
Completed projects
Altersabhängige Expression und Funktion der zellulären "Sauerstoffsensoren" Prolylhydroxylase 1-3 im Herzen
(Applicant
Katschinski, Dörthe M.
)
Bedeutung der Hypoxie-induzierten Genexpression für die Ausbildung einer durch mechanische Last-induzierten Myokardhypertrophie
(Applicant
Katschinski, Dörthe M.
)
Expression, Regulation und Funktion einer hodenspezifischen Isoform des Hypoxie-induzierbaren Faktors-1 alpha
(Applicant
Katschinski, Dörthe M.
)
PASKIN der eukaryotische Verwandte des Sauerstoffsensors FixL der Stickstoff-fixierenden Knöllchenbakterien
(Applicant
Katschinski, Dörthe M.
)
Prolyl-4-hydroxylase domain enzymes and erythropoietin producing mesenchymal stem cell (MSC) like cells in the kidney
(Applicant
Katschinski, Dörthe M.
)
Redox regulation of leukocyte calcium signaling and function
(Applicants
Bogeski, Ivan
;
Niemeyer, Ph.D., Barbara Anne
)
Clinical Research Units
Completed projects
Protektiver Effekt von HIF-1 bei erhöhter mechanischer Belastung des Herzens
(Applicant
Katschinski, Dörthe M.
)
Priority Programmes
Current projects
Harnessing ferroptosis as a potential therapeutic target against melanoma-associated central nervous system metastases
(Applicant
Todoran née Stejerean, Ioana
)
Completed projects
A dual STIM2 redox switch in melanoma immunology
(Applicants
Bogeski, Ivan
;
Hoth, Markus
)
Tuning wavelength and G protein specificty of Melanopsin for optogenetic control of G protein signaling pathways.
(Applicants
Brügmann, Tobias
;
Gerwert, Klaus
;
Herlitze, Stefan
)
Collaborative Research Centres
Current projects
Optogenetic Laryngeal Pacemaking
(Project Heads
Beutner, Dirk
;
Brügmann, Tobias
)
Completed projects
Decoding the functional relevance of compartmentally controlled calcium and redox signaling
(Project Heads
Bogeski, Ivan
;
Niemeyer, Ph.D., Barbara Anne
)
Exploring the role of mitochondrial contact sites on calcium and redox signaling in cancer
(Project Head
Bogeski, Ivan
)
Gq protein activation by atrial stretch in heart failure (HF).
(Project Head
Brügmann, Tobias
)
International Research Training Groups
Completed projects
GRK 1816: Phosphorylation- and Redox-mediated Signalling Mechanisms in the Failing Heart
(Spokesperson
Katschinski, Dörthe M.
)
Research Training Groups
Current projects
GRK 2824: Heart and brain diseases: integrative research across organs
(Spokesperson
Katschinski, Dörthe M.
)
GRK 2978: Understanding and Exploiting Adaptation to Therapy in Gastrointestinal Cancer
(Spokesperson
Heßmann, Elisabeth
)
Completed projects
GRK 288: Structures and Mediators of the Interaction of Cells
(Spokesperson
Jelkmann, Wolfgang
)
