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Project Details

Institution

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Universität Regensburg
Fakultät für Medizin
Lehrstuhl für Experimentelle Medizin und Therapieverfahren

Address Franz-Josef-Strauß-Allee 11
93053 Regensburg
Deutschland

GERiT This institution in GERiT

93053 Regensburg

Projects

Research Grants
- Current projects
- Completed projects
Priority Programmes
- Current projects
  - Modelling and targeting bone metastasis formation in prostate cancer
    (Applicants Guzvic, Ph.D., Miodrag ; Klein, Christoph )
- Completed projects
  - Mechanisms of early metastatic spread: Epigenetic plasticity and selection of advantageous genotypes
    (Applicant Klein, Christoph )
  - Molecular Characterization of Bone Metastasis Founder Cells in Prostate Cancer
    (Applicants Guzvic, Ph.D., Miodrag ; Klein, Christoph )
Research Units
- Completed projects
  - Administration of the FOR
    (Applicant Klein, Christoph )
  - Coordination Funds
    (Applicant Klein, Christoph )
  - Ectopic somatic progression of metastatic breast cancer cells
    (Applicant Klein, Christoph )
  - FOR 2127: Selection and Adaptation during Metastatic Cancer Progression
    (Spokesperson Klein, Christoph )
  - Identification of tumor-cell intrinsic and microenvironmental factors influencing lymph node colonization in melanoma.
    (Applicants Haferkamp, Ph.D., Sebastian ; Werner-Klein, Melanie )
  - Systematic analysis of metastatic cancer: Central mouse and in vitro projects
    (Applicants Braun, Armin ; Klein, Christoph )
CRC/Transregios
- Current projects
  - Disseminated cancer cell-derived extracellular vesicles in early metastatic organ colonisation
    (Project Head Werner-Klein, Melanie )
  - Evolution of systemic cancer: Mapping the acquisition of metastatic traits into cell lineage trees
    (Project Head Klein, Christoph )
  - Functional analysis of Baz2a containing chromatin remodeling complexes in metastasis models
    (Project Heads Hosseini, Hedayatollah ; Längst, Gernot M. )
  - High-throughput screening assays and readouts for targeting metastatic progression
    (Project Heads Gribbon, Ph.D., Philip ; Honarnejad, Kamran ; Klein, Christoph ; Stojanovic Guzvic, Natasa ; Stutz, Andrea ; Wegener, Joachim )
  - Service platform for tracking cancer from early spread at diagnosis to multi-organ manifestation
    (Project Heads Evert, Katja ; Fasching, Peter ; Hartmann, Arndt ; Klein, Christoph )
  - Serviceprojekt
    (Project Head Klein, Christoph )
  - TRR 305: Striking a moving target: From mechanisms of metastatic colonization to novel systemic therapies
    (Spokesperson Klein, Christoph )
Collaborative Research Centres
- Completed projects
  - Genomische Aberrationen und Proteinasespektrum disseminierter Tumorzellen und mikrodissezierter Areale des Primärtumors von humanen Bronchialkarzinomen und autochthonen Maustumoren
    (Project Heads Klein, Christoph ; Passlick, Bernward )
  - Tumor- und Metastasen-initiierende Mutationen beim Mammakarzinom: Identifizierung des abhängigen Phänotyps als Ausgangspunkt für adjuvante Therapien
    (Project Head Klein, Christoph )

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