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Project Details
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Institution
The Scripps Research Institute
Department of Chemistry
Address
10550 North Torrey Pines Road
La Jolla CA 92037
USA
La Jolla CA 92037
Projects
Research Fellowships
Completed projects
Approach to a enedyine biosynthesis tool box through metagenomic and targeted metabolomic analyses of actinomycetes
(Applicant
Crnovcic, Ivana
)
Direct electrochemical functionalizations of unactivated C–H bonds for the late stage modification of complex structures
(Applicant
Hermann, Gary N.
)
Electrochemically enabled (enantioselective) nickel-catalyzed sp³ C-H α-arylation of (a)cyclic heterohydrocarbons
(Applicant
Teske, Johannes
)
Erweiterung des genetischen Codes in vivo: Durch genomische Mutagenese soll die Redundanz des genetischen Codes in E.Coli verringert werden, um Triplets "freizumachen" für die Codierung von unnatürlichen (z.B. fluoreszenten) Aminosäuren,
(Applicant
Jahnz, Michael
)
Genetically Encoding Photocaged Amino Acids in Yeast and Mammalian Cells for in vivo Studies of Caspase-Mediated Apoptotic Cell Death
(Applicant
Grünewald, Jan
)
Genetische Manipulation des C-1027-Biosyntheseclusters und chemische Untersuchung dieser Mutanten sowie die genetische Untersuchung der Neocarzinostatin-Biosynthese
(Applicant
Ingenhorst, Gudrun
)
Novel synthetic strategy for the formation of C-C bonds using alkyl boronic esters
(Applicant
Tian, Maoqun
)
Small Molecule-Mediated Cleavage of RNA In Cells. Application to Incurable Human Genetic Disease
(Applicant
Ursu, Andrei
)
Stereoselective reactions on the primordial Earth
(Applicant
Legnani, Luca
)
Synthese von alpha-D-Glucosamin-Derivaten als antibiotisch wirksame übergangszustandsanaloge Transglycosidase-Inhibitoren
(Applicant
Gosberg, Andreas
)
Totalsynthese of the natural substance Aconitin
(Applicant
Weickgenannt, Andreas
)
Totalsynthese von Maoecrystal V
(Applicant
Schöne, Niklas
)
Total Synthesis of the Terpenoid Phthalazinone Azamerone
(Applicant
Gulder, Tanja
)
Towards an understanding of ß-sheet folding and misfolding
(Applicant
Jäger, Marcus
)
Two-Phase Taxane Total Synthesis
(Applicant
Prochnow-Sturm, Insa
)
WBP Fellowship
Current projects
Asymmetric α-Hydrobenzylation of Enamines to Form Quaternary Carbons: Towards a New Class of MRSA-Targeting Antibiotics
(Applicant
Ahlburg, Nils Lennart
)
Electrodecarboxylative Amination of Malonates Enables the Enantioselective Formation of Non-Natural Amino Acids
(Applicant
Goebel, Jonas Felix
)
Elucidating the Biosynthesis of the Core Structure of Enediyne Natural Products
(Applicant
Lauterbach, Lukas
)
Evaluation of electrophiles for the development of covalent RNA-binders
(Applicant
Zanon, Patrick
)
Completed projects
Novel actinobacterial TrmD inhibitors to combat Gram-negative pathogens
(Applicant
Bader, Chantal
)
Targeting breast cancer via site-specific antibody-drug conjugates based on biosynthetically modified enediyne natural products
(Applicant
Kiefer, Alexander
)
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