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Institution

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Universitätsklinikum Köln
Department of Translational Genomics

Address Weyertal 115b
50931 Köln
Deutschland

GERiT This institution in GERiT

50931 Köln

Projects

Research Grants
- Current projects
  - Understanding tumor progression and therapy resistance in Head and Neck Squamous Cell Carcinomas
    (Applicants Abedpour, Ph.D., Nima ; George, Julie )
- Completed projects
  - Ein Chemical-Genomics Ansatz für die Identifizierung von Onkogenabhängigkeit beim kleinzelligen Bronchialkarzinom
    (Applicant Thomas, Roman )
  - Targeting ferroptosis pathway vulnerability in small cell lung cancer (SCLC)
    (Applicant von Karstedt, Silvia )
Priority Programmes
- Current projects
  - cPLA2α-mediated ferroptosis regulation in small cell lung cancer (SCLC)
    (Applicant von Karstedt, Silvia )
Collaborative Research Centres
- Current projects
  - Bioinformatics and Data management
    (Project Heads Abedpour, Ph.D., Nima ; Peifer, Martin ; Valencia-Schneider, Monica )
  - Cell Death Assessment Unit
    (Project Heads Fritsch, Melanie ; von Karstedt, Silvia ; Kashkar, Hamid )
  - Central administration
    (Project Head Thomas, Roman )
  - Exploiting innate nucleic acid receptor pathways to enhance immunotherapy in SCLC
    (Project Head Brägelmann, Johannes )
  - How cell death shapes tumor evolution during carcinogenesis
    (Project Heads Berg, Johannes ; von Karstedt, Silvia )
  - Identification and characterization of molecular vulnerabilities in SCLC
    (Project Heads Beleggia, Filippo ; Reinhardt, Christian ; Wunderlich, Frank Thomas )
  - Immuno-editing via programmed cell death in SCLC
    (Project Head von Karstedt, Silvia )
  - Inflammatory signalling in ferroptotic cell death
    (Project Head von Karstedt, Silvia )
  - Mechanisms of drug sensitivity and resistance in SCLC
    (Project Heads George, Julie ; Thomas, Roman )
  - Molecular characterization of the immunogenic profile in SCLC tumors
    (Project Head George, Julie )
  - Research data management, analysis and bioinformatics support
    (Project Heads Hofmann, Kay ; von Karstedt, Silvia ; Wesner, Stefan )
  - SCLC response to chemotherapy and ionizing 𝛾-radiation
    (Project Head Cartolano, Maria )
  - SFB 1399: Mechanisms of drug sensitivity and resistance in small cell lung cancer
    (Spokesperson Thomas, Roman )
  - The role of ferroptosis in diffuse large B-cell lymphoma subtypes
    (Project Head von Karstedt, Silvia )
- Completed projects
  - Validating therapeutic anti-angiogenic targets by a combined chemical genetics and imaging approach
    (Project Heads Thomas, Roman ; Ullrich, Roland Tillmann ; Wolf, Jürgen )

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