Project Details

Professor Dr. Mathias Heikenwälder

Address Eberhard Karls Universität Tübingen
Medizinische Fakultät und Universitätsklinikum Tübingen
M3 Research Centre: Malignom, Metabolome and Microbiome
Otfried-Müller-Straße 37
72076 Tübingen

ORCID-ID 0000-0002-3135-2274

Projects

As Applicant
- Current projects
  - How danger signals control an immunological „point-of-no-return“ in the MASLD-HCC transition (Research Units)
- Completed projects
  - Activation of alternative NF-kB signaling in the stomach: link to H. pylori virulence factors and effect on gastric inflammation and gastric pathogenesis (Research Grants)
  - The role of chronic neuroinflammation in the pathogenesis of CNS lymphoma (Research Grants)
As Participating Researcher
- Current projects
  - EXC 2124: Controlling Microbes to Fight Infections (CMFI) (Clusters of Excellence (ExStra))
  - EXC 2180: Image-guided and Functionally Instructed Tumor Therapies (iFIT) (Clusters of Excellence (ExStra))
As Project Head
- Current projects
  - Investigating the role of platelets in psoriasis in the context of systemic metabolic inflammation (CRC/Transregios)
  - Molecular, spatial, and cellular mechanisms of necro-inflammation-induced metabolic reprogramming in MASH (CRC/Transregios)
  - Targeting the parenchymal and immune proto-oncogenic ER-stress/ ATF6 - axis in liver cancer (Collaborative Research Centres)
- Completed projects
  - Adoptive T cell therapy to treat hepatocellular carcinoma (CRC/Transregios)
  - Role of platelets in control and clearance of hepatitis B virus infection via modulation of liver tissue environment and metabolism (CRC/Transregios)
  - Platelet aggregation and activity in steatosis-HCC (CRC/Transregios)
  - Control of TCR-signalling specificity to combat liver cancer in the context of immunotherapy (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Notch signaling in liver cell plasticity, development, and regeneration (Research Grants)
As Co-Investigator
- Completed projects
  - In vivo staging of alcoholic and non-alcoholic liver disease (Research Grants)

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Hauptnavigation

Professor Dr. Mathias Heikenwälder

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Mathias Heikenwälder

Additional Information

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