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Project Details

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Professor Dr. Friedhelm Hildebrandt

Address Boston Children's Hospital
Division of Nephrology
300 Longwood Avenue
Boston MA 02115
USA

Projects

As Applicant
- Completed projects
  - Fibronektin-Glomerulopathie: Identifizierung und molekulare Charakterisierung des verantwortlichen Gens (Research Grants)
  - Elucidating Nephrocystin Function by Targeted Disruption of the NPHP1 Gene (Research Grants)
  - Pädiatrie (Heisenberg Fellowships)
As Project Head
- Completed projects
  - Elucidating novel mechanisms of focal adhesion signaling by targeted disruption of the mouse nephrocystin gene (Kurztitel: Nephrocystin signaling) (Collaborative Research Centres)
As Host
- Current projects
- Completed projects
  - Characterization of novel single gene causes of nephrotic syndrome in Drosophila (Research Fellowships)
  - Molecular genetic causes of renal ciliopathies - a candidate gene approach including the survivin signaling pathways (Research Fellowships)
  - Identification of CAKUT-associated genes using a worldwide patient-cohort and high-throughput methods for genetic analysis (Research Fellowships)
  - Effect of Rho GTPase-regulating protein DLC1 on podocytes (Research Fellowships)
  - Discovery and functional characterization of full-penetrance single-gene causes of steroid-resistant nephrotic syndrome and focal segmental glomerulosclerosis (Research Fellowships)
  - Disease mechanisms of ZMYM2 mutations, a new monogenic cause for congenital anomalies of the kidney and urinary tract (WBP Fellowship)
  - The effect on the small GTPase CDC42 by NOS1AP SRNS mutations (WBP Fellowship)
As Co-Applicant
- Completed projects
  - Gen-Identifizierung und -Funktionsanalyse bei autosomal-dominanter "Medullary Cystic Kidney Disease (MCKD) (Research Grants)

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