Project Details

Professorin Dr. Elke Beate Krüger

Address Universitätsmedizin Greifswald
Institut für Medizinische Biochemie und Molekularbiologie
Ferdinand-Sauerbruch-Straße DZ 7
17489 Greifswald

Projects

As Applicant
- Current projects
  - The function and functional interaction of APN / CD13 and PAR2 in the development and progression of colon cancer (Research Grants)
  - Dissecting the mechanisms linking proteasome function to mitochondrial proteostasis (Priority Programmes)
  - Deciphering the link between proteostatic control by the ubiquitin-proteasome system and ferroptosis in lymphocytes (Priority Programmes)
- Completed projects
  - Impact of the proteasomal immune adaptation on the early immune response to viral infection (Research Grants)
  - Transcription factor 11 (TCF 11) is a transcriptional regulator of proteasome subunit genes - what in turn regulates TCF 11 activation? (Research Grants)
As Leader
- Completed projects
  - Hochauflösendes Flüssigkeitschromatographie-Massenspektrometriesystem (LC-MS) (Major Research Instrumentation)
As Participating Researcher
- Current projects
  - GRK 2719: Proteases in pathogen and host: importance in inflammation and infection – RTG-PRO (Research Training Groups)
As Project Head
- Completed projects
  - The role of immunoproteasomes and the ubiquitin system in inflammatory processes in mouse models of Alzheimer's and Parkinson's disease (CRC/Transregios)
  - Regulation of proteasome modules (Collaborative Research Centres)
  - Elucidating the redox-proteolysis switch for transcriptional induction of the ubiquitin proteasome system (UPS) in space and time (CRC/Transregios)
  - Impact of proteostasis and the ubiquitin proteasome system on myeloid cell function in the CNS (CRC/Transregios)
As Participating Person
- Completed projects
  - Analyse der molekularen und biochemischen Mechanismen der Proteasomassemblierung (Research Grants)
  - The function of the Ubiquitin-Proteasome-System (UPS) in MHC class I antigen processing in target cells and maturing human dendritic cells (hDCs). (Research Grants)
As Ehemalige Antragstellerin
- Completed projects
  - Adaptation of proteasome composition in inflammatory response - the impact of the hybridproteasome (Research Grants) to 2/2017
As Co-Investigator
- Current projects
  - Meeting the Challenges of Chronic Age-Related Diseases in Rural Areas (Research Grants)

Servicenavigation

Hauptnavigation

Professorin Dr. Elke Beate Krüger

Additional Information

Servicenavigation

Hauptnavigation

Professorin Dr. Elke Beate Krüger

Additional Information

Textvergrößerung und Kontrastanpassung