SFB 1348:  Dynamic cellular interfaces: formation and function

• Subject Area: Biology
• Term: since 2018
• Website: Homepage
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 386797833

No abstract available

• DFG Programme: Collaborative Research Centres

Current projects

• A01 - The role of protein-lipid interactions for protein segregation in the yeast plasma membrane (Project Heads Heuer, Andreas ;  Wedlich-Söldner, Roland )
• A02 - Local signaling for tight coupling of synaptic exo- and endocytosis (Project Head Klingauf, Jürgen )
• A05 - Lipid-mediated activation of protein kinases during cell polarization (Project Head Krahn, Ph.D., Michael )
• A06 - Force-control in neurons via curved membrane nanodomains (Project Head Galic, Milos )
• A07 - Regulation of growth factor signaling by the nanoscale presentation of the extracellular matrix (Project Head Trappmann, Britta )
• A08 - Molecular parameters for the dynamic assembly of Hedgehog signaling platforms (Project Head Grobe, Kay )
• A09 - Regulation and execution of vesicle formation in clathrin-independent endocytosis (Project Head Schelhaas, Mario )
• A10 - Specification and dynamic interactions of arterial progenitor cells (Project Heads Adams, Ralf H. ;  Pitulescu, Mara E. )
• A11 - Regulation of plasma membrane supramolecular functional units by late endosomal sorting and transport (Project Heads Glorius, Frank ;  Rescher, Ursula )
• A12 - Integrin subtype-specific organization and force transduction (Project Heads Grashoff, Carsten ;  Miroshnikova, Ph.D., Yekaterina )
• A13 - Lipid storage organelles in formation of polarized cellular interfaces during cell division and cell fusion (Project Heads Bohnert, Maria ;  Büttner, Sabrina )
• A14 - Dynamic and spatiotemporal control of Notch and Plexin signaling for assembling precise multicellular structures (Project Heads Sánchez, Maria Florencia ;  Wegner, Seraphine )
• A15 - Structural insights into the complex interplay between latrotoxin and the cell adhesion receptors neurexin and latrophilin (Project Head Gatsogiannis, Christos )
• B06 - Cell-cell interactions controlling organ shape (Project Heads Raz, Erez ;  Tarbashevich, Katsiaryna )
• B09 - Morphogenesis of the trophoblast lineage during blastocyst to egg cylinder transition (Project Head Bedzhov, Ivan )
• B11 - Remodeling of tricellular junctions controls paracellular transport (Project Head Luschnig, Stefan )
• B13 - Mechanochemical coordination of tissue patterning and cellular dynamics (Project Heads Biggs, Ph.D., Leah ;  Wickström, Sara A. )
• B14 - Mechanisms of neutrophil invasion across cellular membranes (Project Heads Lämmermann, Ph.D., Tim ;  Stegmeyer, Rebekka )
• B15 - The role of latrophilin in contact-stimulated mesenchymal cell migration and tissue sculpting (Project Head Bischoff, Maik Christian )
• MGK - Integrated Research Training Group (Project Heads Bohnert, Maria ;  Büttner, Sabrina ;  Luschnig, Stefan )
• Z - Central Tasks (Project Heads Klämbt, Christian ;  Luschnig, Stefan )

Completed projects

• A03 - Dynamic regulation of synaptic calcium channels by neurexins (Project Head Missler, Markus )
• A04 - Membrane platforms in regulated secretion from endothelial cells (Project Head Gerke, Volker )
• B01 - VE-cadherin modifications and binding partners regulate endothelial junctions (Project Head Vestweber, Dietmar )
• B03 - High-resolution analysis of membrane domain formation during neuronal polarization (Project Heads Busch, Karin ;  Püschel, Andreas )
• B04 - Membrane remodeling and severing during dendrite pruning in Drosophila neurons (Project Head Rumpf, Sebastian )
• B05 - Localized FGF-receptor signaling controls differentiation of wrapping glial cells (Project Head Klämbt, Christian )
• B07 - Morphogenetic mechanisms during lymphatic vessel formation (Project Head Kiefer, Friedemann )
• B08 - Local cues trigger changes in the migratory behavior of lymphangioblasts (Project Head Schulte-Merker, Stefan )
• B10 - Spatiotemporal regulation of secretory lysosome trafficking controls epithelial tube fusion (Project Head Luschnig, Stefan )
• B12 - Delineating functional roles between the interstitial matrix and the basement membrane during cardiac valve formation (Project Head Gunawan, Ph.D., Felix )

• Applicant Institution: Universität Münster
• Participating University: Technische Universität Dortmund
• Participating Institution: Max-Planck-Institut für molekulare Biomedizin
• Spokespersons: Professor Dr. Christian Klämbt, until 12/2023; Professor Dr. Stefan Luschnig, since 1/2024