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Institution

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Albert-Ludwigs-Universität Freiburg
Klinik für Urologie
Arbeitsgruppe Hormone Dependent Cancer

Address Breisacher Straße 66
79106 Freiburg
Deutschland

GERiT This institution in GERiT

79106 Freiburg

Projects

Research Grants
- Current projects
  - Understanding the relevance of RAI2 activity in emerging therapy-resistance of castration-resistant prostate cancer
    (Applicants Pantel, Klaus ; Werner, Stefan )
- Completed projects
Priority Programmes
- Completed projects
  - Modulation circadianer Regulationsmechanismen durch den nukleären Orphan Rezeptor RZRbeta
    (Applicant Schüle, Roland )
Reinhart Koselleck Projects
- Completed projects
  - Control of histone demethylase activity: An innovative therapeutic concept to fight hormone refractory prostate cancer
    (Applicant Schüle, Roland )
Workshops for Early Career Investigators
- Current projects
  - Urologial Diseases in a Aging Society: From Genetic to Medical Csre (UroAgeCare)
    (Applicant Schüle, Roland )
Research Units
- Current projects
  - FOR 2674: Aging-related epigenetic remodeling in acute myeloid leukemia
    (Spokesperson Lübbert, Ph.D., Michael )
  - FOR 5476: UcarE - Urothelial Carcinoma Epigenetics
    (Spokesperson Frew, Ian )
  - P5: Dissection of KMT9 biology in urothelial carcinoma
    (Applicant Schüle, Roland )
  - The role of the histone demethylase LSD1 in the pathogenesis of AML
    (Applicants Pahl, Heike L. ; Schüle, Roland )
- Completed projects
  - FOR 2438: Cell Plasticity in Colorectal Carcinogenesis
    (Spokesperson Greten, Florian R. )
Collaborative Research Centres
- Current projects
  - Central Tasks of the Collaborative Research Centre
    (Project Head Schüle, Roland )
- Completed projects
  - Assembly and signal-mediated regulation of the androgen receptor/LSD1 histone demethylation complex
    (Project Head Schüle, Roland )
  - Characterisation of the lysine methyltransferases KMT9 and KMT10
    (Project Head Schüle, Roland )
  - Control of adipogenesis by the signal-regulated INHAT-repressor NIR
    (Project Head Schüle, Roland )
  - Funktionelle Charakterisierung des Androgenrezeptor Koaktivatorproteins FHL2
    (Project Head Schüle, Roland )
  - SFB 992: Medical Epigenetics (MEDEP) - From Basic Mechanisms to Clinical Applications
    (Spokesperson Schüle, Roland )
  - Strategien zur gezielten Modulation der transkriptionellen Aktivität des Tumorsuppressorproteins WT1
    (Project Head Schüle, Roland )
  - The KMT9 protein machinery is a novel chromatin writer
    (Project Head Schüle, Roland )
  - The novel arginine methyltransferase PRMT10 controls tumor growth and metastatic disease
    (Project Head Schüle, Roland )
Clusters of Excellence
- Completed projects
  - EXC 294: Centre for Biological Signalling Studies (bioss) - From Analysis to Synthesis
    (Spokesperson Reth, Michael )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2189: CIBSS - Centre for Integrative Biological Signalling Studies
    (Spokespersons Driever, Wolfgang ; Hunte, Carola ; Kleine-Vehn, Jürgen ; Weber, Wilfried )

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