Project Details

Professor Dr. Alexander Pfeifer

Address Rheinische Friedrich-Wilhelms-Universität Bonn
Medizinische Fakultät
Institut für Pharmakologie und Toxikologie
Venusberg-Campus 1
53127 Bonn

Projects

As Applicant
- Completed projects
  - Lentiviral gene transfer into murine embryonic stem cells: Generation of transgenic animals (Research Grants)
  - Entwicklung eines Ansatzes zur Therapie neurodegenerativer Erkrankungen auf Basis von RNA-Interferenz am Beispiel der Prionerkrankungen (Research Grants)
  - The function of VASP in brown fat (Research Grants)
  - Magnetic nanoparticles assisted modulation of the vascular cGMP system (Research Units)
  - Common Resources (Research Units)
  - Regulation of Activin Receptor-like kinase 7 (ALK7) by cGMP in adipocytes (Research Grants)
  - Function of cGMP/PKGI signaling in osteogenic differentiation and disease (Research Grants)
  - Impact of Gq signaling in the brown adipose tissue (Research Units)
As Spokesperson
- Current projects
  - TRR 333: Brown and Beige Fat – Organ Crosstalk, Signaling and Energetics (BATenergy) (CRC/Transregios)
- Completed projects
  - FOR 917: Nanoparticle-based Delivery of Innovative Therapies (NanoTarget) (Research Units)
  - GRK 1873: Pharmacology of 7TM-Receptors and Downstream Signalling Pathways (Research Training Groups)
As Project Head
- Current projects
  - Interactions of endothelium and adipocytes during thermogenic adaptation (CRC/Transregios)
  - Regulation and adaptation of G-protein coupled receptors/adenylyl cyclase/cAMP signaling networks in brown/beige AT (CRC/Transregios)
  - Functional Proteomics/Metabolomics/Lipidomics and Human Adipocyte Unit (CRC/Transregios)
  - Central Tasks (CRC/Transregios)
  - The spatiotemporal signature of cAMP signaling in brown/beige adipocytes and its interaction with the chemokine-cytokine network (Collaborative Research Centres)
  - Influence of perivascular brown adipose tissue on aortic valve disease (CRC/Transregios)
  - Extracellular vesicles and regulatory RNAs as intercellular messengers in aortic disease (CRC/Transregios)
  - Purinergic crosstalk in thermogenic fat – Regulation of adenosine release by ENT1 (CRC/Transregios)
- Completed projects
  - The role of cyclic nucleotides in the regulation of adipose tissue resident myeloid cells (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Viral strategies for xenotransplantation (Research Units)

Servicenavigation

Hauptnavigation

Professor Dr. Alexander Pfeifer

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Alexander Pfeifer

Additional Information

Textvergrößerung und Kontrastanpassung