Project Details

Professor Dr. Oliver T. Fackler, Ph.D.

Address Universitätsklinikum Heidelberg
Zentrum für Infektiologie
Sektion Integrative Virologie
Im Neuenheimer Feld 344
69120 Heidelberg

Projects

As Applicant
- Current projects
  - Characterization of HIV infection in resting CD4 T-cells (Research Grants)
  - Mechanisms of actin polymerization in T lymphocyte nuclei (Research Grants)
  - Role of lncRNAs in cell activation, actin remodeling and HIV latency in CD4 T lymphocytes (Research Grants)
- Completed projects
  - Analyse der molekularen Mechanismen des Pathogenitätsfaktors Nef des Humanen Immundefizienzvirus Typ 1 (HIV-1) (Independent Junior Research Groups)
  - Design und Charakterisierung eines Moleküls zur Inhibierung des HIV Pathogenesefaktors Nef (Research Grants)
  - Rho GTPases and Diaphanous related Formins in HIV-1 replication (Priority Programmes)
  - Regulationsmechanismen und physiologische Funktion des Diaphanous Formins FHOD1 (Research Grants)
  - Mechanisms of cell motility inhibition by the HIV-1 pathogenesis factor NEF (Research Grants)
  - Role of the Diaphanous Formin FHOD1 and its interaction with nesprin-2-giant in nuclear migration (Research Grants)
  - Characterization of the antiviral immunity factor CD317/tetherin (Research Grants)
  - Antagonism of Host Cell Restriction and Sensing by HIV-1 Nef (Priority Programmes)
  - Coordination Funds (Priority Programmes)
  - The role of TREX1 for innate sensing human endogenous retroviruses (Priority Programmes)
As Spokesperson
- Completed projects
  - GRK 1188: Quantitative Analysis of Dynamic Processes in Membrane Transport and Translocation (Research Training Groups)
  - SPP 1923: Innate Sensing and Restriction of Retroviruses (Priority Programmes)
As Project Head
- Current projects
  - HIV-1 spread in complex cell systems (Collaborative Research Centres)
- Completed projects
  - Nef and Lipid Rafts: Functional Coordination of the HIV Pathogeneticity factor during particle release and TCR Signaling (CRC/Transregios)
  - Modulation of architecture and function of the immunological synapse by the HIV pathogenesis factor Nef (Collaborative Research Centres)
  - Membrane microdomain interactions of the HIV-1 pathogenicity factor Nef (CRC/Transregios)
As Co-Investigator
- Completed projects
  - Mechanisms of inflammasome activation and pyroptosis induction by HIV (Priority Programmes)

Servicenavigation

Hauptnavigation

Professor Dr. Oliver T. Fackler, Ph.D.

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Oliver T. Fackler, Ph.D.

Additional Information

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