SPP 1089:  Novel Vaccination Strategies

• Subject Area: Medicine
• Term: from 2000 to 2006
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5470124

No abstract available

• DFG Programme: Priority Programmes

Projects

• Dendritic cell-based vaccination against infection: analysis of the parameters determining the protective of dendritic cells in the modell of leishmaniasis (Applicant Moll, Heidrun )
• Development of optimized adjuvant vectors for DNA vaccination (Applicant Haas, Jürgen )
• Development of protein-based subunit vaccines against Streptococcus pneumoniae (Applicant Chhatwal, Gursharan Singh )
• Development of Yersinia carrier systems for vaccination and investigation of cell-mediated Immune responses (Applicant Autenrieth, Ingo Birger )
• Development of Yersinia oral live carrier vaccine: Influence of the type III- secret/translocated effector proteins (Yops) on the immune response (Applicant Heesemann, Jürgen )
• Entwicklung einer oralen Amöbiasisvakzine unter Verwendung rekombinanter, attenuierter Yersinia enterocolitica (Applicant Tannich, Egbert )
• Generation and characterization of recombinant coxsackievirus replicons for prevention of virus-induced heart disease (Applicant Henke, Andreas )
• Identification of low-molecular mass ligands for targeting of subunit vaccines to Peyer`s patch M cells (Applicant Frey, Andreas )
• Identification of protective T-cell epitopes from intracellular bacteria from heat schock protein/peptide complexes (Applicant Kaufmann, Stefan H.E. )
• Immunisation protokolls utilising cpG-DNA coupled proteins for the activation of Dendritic Cells (DCs) with special emphasis on the cross-presentation/priming ability of plasmacytoid DCs (Applicant Wagner, Hermann )
• Impact of compartimentalized antigen expression by Mycobacterium bovis Bacille Calmette-Guérin (BCG) on the induction of T-cell mediated immunity (Applicant Hess, Jürgen )
• Induction of mucosal immune responses by the AIDA autotransporter-mediated presentation of heterologous antigenes in (commensal) live vectors (Applicant Schmidt, Marcus Alexander )
• Kombinierte CpG-Oligodeoxynukleotid/Lipopeptid Liposomen als neuer immunmodulatorischer Impfstoff gegen Hepatitis C Virus Infektion (Applicant Spengler, Ulrich )
• Kombinierte CpG-Oligodeoxynukleotid/Lipopeptid Liposomen als neuer immunmodulatorischer Impfstoff gegen Hepatitis C Virus Infektion (Applicant Will, Hans )
• Live vaccines based on virulence-attenuated Listera monocytogenes carrying novel plasmid vectors - a comparison of efficiency (Applicant Goebel, Werner )
• Native display of Borrelia antigens on the surface of hepatitis B virus capsids: Improved prophylactic and potential therapeutic vaccines against Lyme disease (Applicant Nassal, Michael )
• Native display of Borrelia antigens on the surface of hepatitis B virus capsids: Improved prophylactic and potential therapeutic vaccines against Lyme disease (Applicant Simon, Markus Michael )
• Oligodesoxynucleotides as adjuvants: Use in prophylactic and therapeutic vaccines (Applicant Zimmermann, Stefan )
• Oligodesoxynucleotides as adjuvants: Use in prophylactic and therapeutic vaccines (Applicant Heeg, Klaus Michael )
• Optimisation of host immune responses against vaccine antigens (Applicant Guzman, Ph.D., Carlos Alberto )
• Optimisation of recombinant Helicobacter pylori Ghosts for vaccination in H. pylori mouse and Mongolian Gerbil models (Applicant Haas, Rainer )
• Optimization of Salmonella-mediated oral vaccination (Applicant Weiß, Siegfried )
• Protective mechanism of Salmonella-based vaccination against Helicobacter pylori in mice (Applicant Meyer, Thomas F. )
• Recombinant live herpesvirus vaccines (Applicant Koszinowski, Ulrich H. )
• Recombinant Respiratory Syncytial Virus Vectors for Immunization of Respiratory Epithelia (Applicant Conzelmann, Karl-Klaus )
• Role of dendritic cells as adjuvants and carrier of microbial antigens in mucosal immunization (Applicant Beuscher, Horst Ulrich )
• Salmonella as a live carrier for recombinant vaccines: intracellular activated promoters (Applicant Hensel, Michael )
• Salmonella type III-mediated antigen targeting to induce cellular immunity: characterzition of effector and memory T cell populations after oral vaccination (Applicant Rüssmann, Holger )

• Spokesperson: Professor Dr. Stefan H.E. Kaufmann