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Characterization of the gut mucosa transcriptome in extraintestinal cancer and ICI-responders & Development of a gut mucosa-based biomarker score to predict response to gut microbiome-based interventions
Applicants Conrad Rauber , Maria Paula Roberti
Subject Area Gastroenterology
DFG Programme Research Grants Term Since 2024
In recent years, the link between the gut microbiome and a variety of human diseases has been increasingly recognized. In
extraintestinal tumor diseases, we ...
Comparative red blood cell physiology: uncovering novel cellular mechanisms to predict the impacts of climate change on fishes
Applicant Till Harter
Subject Area Animal Physiology and Biochemistry
DFG Programme Independent Junior Research Groups Term Since 2024
Anthropogenic climate change poses an immediate threat to aquatic ecosystems around the globe, including the ecologically,
culturally, and ...
Comprehensive refinement of advanced magnetic resonance image acquisition and post-processing techniques to quantify glycosaminoglycan content as a biomarker of lumbar intervertebral disc composition.
Applicants Daniel Abrar , Timm Filler , Anja Müller-Lutz
Subject Area Radiology
DFG Programme Research Grants Term Since 2024
Back pain is a very common condition and affects more than 600 million patients worldwide. The prevalence in Germany was greater
than 60% in the last 12 ...
Applicant Ulrich Kleinekathöfer
Subject Area Biophysics
DFG Programme Research Grants Term Since 2024
n the broad portfolio of nanopore sensing applications, the identification of chiral peptide isoforms is an important one,
relevant for example to disease ...
Applicant Christoph Stampfer
Subject Area Experimental Condensed Matter Physics
Subproject of SPP 2244
DFG Programme Priority Programmes Term Since 2024
The aim of this project is to achieve an in-depth understanding of gate-defined charge carrier confinement in van der Waals
(vdW) heterostructures with ...
Leader Michael Kovermann
Review Board Basic Research in Biology and Medicine
DFG Programme Major Research Instrumentation Term in 2024
The major equipment applied for aims to enable the execution of research projects at the NMR core facility that possess highest
relevance. With this investment
Contribution of SERCA2, RyR2, NCX1 and PMCA to excitation-contraction coupling in human cardiomyocytes – tackling an old question with modern technologies
Applicants Torsten Christ , Thomas Eschenhagen
Subject Area Pharmacology
DFG Programme Research Grants Term Since 2024
The central role of calcium for heart contraction is established since the pioneering work of Sydney Ringer. Textbooks summarize
the process (simplified) as ...
Contribution to automated modular modeling, simulation and design of power electronic converters by means of an open-source software/hardware kit
Applicants Frank Schafmeister , Oliver Wallscheid
Subject Area Electrical Energy Systems, Power Management, Power Electronics, Electrical Machines and Drives
DFG Programme Research Grants Term Since 2024
Power electronic converters fulfill a multitude of tasks in heterogeneous applications and are a key technology of the modern
industrial society. For the ...
Applicants Hartmut Löwen , Nicolas Vogel ( in cooperation with Liesbeth Janssen )
Subject Area Thermodynamics and Kinetics as well as Properties of Phases and Microstructure of Materials
DFG Programme Research Grants Term Since 2024
Microgel particles, which can change their volume and physicochemical characteristics by external stimuli, such as temperature
or light, provide excellent ...
Applicants Korshi Dosoo , Marketa Preininger Svobodova
Subject Area Egyptology and Ancient Near Eastern Studies
DFG Programme Research Grants Term Since 2024
Coptic private ritual – "magical" – manuscripts provide deep insights into the hopes, fears, and beliefs of people in Late
Antique and early Islamic Egypt (ca.
Applicants Thomas Doert , Dmytro Inosov
Subject Area Experimental Condensed Matter Physics
DFG Programme Research Grants Term Since 2024
Hydroxide perovskites represent a rich class of materials that were recently demonstrated to host correlated proton disorder,
similar to that known in ...
Correlating eIF4A conformational dynamics with eIF4A-, eIF4B-, and eIF4G-dependence and translation efficiencies of yeast mRNAs
Applicant Dagmar Klostermeier
Subject Area Biochemistry
DFG Programme Research Grants Term Since 2024
Translation of eukaryotic mRNAs starts with the recognition of the 5’-cap by eIF4F, a complex of the cap-binding protein eIF4E,
the scaffold protein eIF4G, and
Applicant Wouter Raymond Jolie
Subject Area Experimental Condensed Matter Physics
Subproject of SPP 2244
DFG Programme Priority Programmes Term Since 2024
A plethora of many-body ground states can emerge when interfacing correlated two-dimensional materials, depending on the electronic
properties of the two ...
Leader Sebastian Gönnenwein
Review Board Condensed Matter Physics
DFG Programme Major Research Instrumentation Term in 2024
Experiments in large magnetic fields and at low temperatures are of fundamental importance for the investigation of magnetic
thin films and heterostructures. ...
Cyclic deformation behavior and macroscopic constitutive law of textured Magnesium sheet for multiaxial loading under consideration of microstructural deformation mechanisms
Applicants Otto Huber , Ulrich Prahl
Subject Area Mechanical Properties of Metallic Materials and their Microstructural Origins
DFG Programme Research Grants Term Since 2024
The aim of this project is the development of a scale-spanning 3D continuum mechanical material model for cyclic stresses
of textured wrought magnesium alloys.
Applicants Stefan Mathias , Marcel Reutzel
Subject Area Experimental Condensed Matter Physics
Subproject of SPP 2244
DFG Programme Priority Programmes Term Since 2024
We aim to explore the energetics, dynamics, transport properties and correlated interactions of intralayer, hybrid and interlayer
excitons in two-dimensional ...
Deciphering Endosomal Recycling Pathways: Insights into Protein and Lipid Sorting in the Endo-Lysosomal System
Applicant Florian Fröhlich
Subject Area Biochemistry
DFG Programme Research Grants Term Since 2024
Lysosomes and vacuoles play a crucial role in the degradation of intracellular and extracellular material. The function of
lysosomes depends on two classes of ...
Applicant Christian Michael Grimm
Subject Area Pharmacology
DFG Programme Research Grants Term Since 2024
In recent years endolysosomes emerged as important intracellular Ca2+ signaling hubs and Ca2+ release from endolysosomes proved
to be of significant ...
Applicant Tamara Mikeladze-Dvali
Subject Area Cell Biology
DFG Programme Research Grants Term Since 2024
Centrosomes are the main microtubule organizing centers of animal cells which ensure spindle bipolarity during cell division.
An error-free regulation of ...
Deciphering the role of stromal IL36R signalling for the resolution of intestinal inflammation and fibrosis
Applicants Kristina Koop , Clemens Neufert
Subject Area Gastroenterology
DFG Programme Research Grants Term Since 2024
Failure to resolve intestinal inflammation is a key feature of patients with inflammatory bowel disease (IBD) and can promote
long-term complications such as ...
Delineating white matter phenotypes of psychomotor functioning in large-scale cohorts of healthy individuals and patients with psychiatric disorders across the life span
Applicants Dusan Hirjak , Klaus Maier-Hein
Subject Area Biological Psychiatry
DFG Programme Research Grants Term Since 2024
Aberrant psychomotor functioning in terms of muscular hand weakness, sedentary behavior, psychomotor slowing, apathy, anxiety
and cognitive impairment is a ...
Deuteronomistic Historiography - a phantom of scholarly debate? The impact of deuteronomistic redactions on the development of the Former Prophets
Applicant Sarah Schulz
Subject Area Protestant Theology
DFG Programme Heisenberg Grants Term Since 2024
The precondition for a Heisenberg Programme funding is high scientific quality and originality of the research project at
international level and suitability ...
Development of adhesion models taking into account surface topographies and frictional power in dry wheel-rail contact on a single-wheel roller rig
Applicant Christian Schindler
Subject Area Engineering Design, Machine Elements, Product Development
DFG Programme Research Grants Term Since 2024
A central field of research in rail vehicle technology deals with the forces between wheel and rail and the resulting forces,
stresses and deformation of the ...
Development of a framework for adaptive operation and maintenance strategies by means of artificial intelligence
Applicant Martin Dazer
Subject Area Engineering Design, Machine Elements, Product Development
DFG Programme Research Grants Term Since 2024
For manufacturers and operators of technical systems, topics such as resource efficiency, sustainability, cost efficiency,
safety, but also availability and ...
Development of pre-stall perturbations in transonic, multi-stage axial compressors under engine-specific conditions
Applicant Marcel Stößel
Subject Area Hydraulic and Turbo Engines and Piston Engines
DFG Programme Research Grants Term Since 2024
This study intends to improve and extend the understanding of the origin and development of pre-stall perturbations in axial,
multi-stage, transonic engine ...