Go directly to content Go directly to font size and contrast

Project Details

Institution

Print View

Rheinische Friedrich-Wilhelms-Universität Bonn
Medizinische Fakultät
Institut für Klinische Chemie und Klinische Pharmakologie

Address Venusberg-Campus 1
53127 Bonn
Deutschland

GERiT This institution in GERiT

53127 Bonn

Projects

Research Grants
- Current projects
  - Nuclear receptors as metabolic relays of ILC2-mediated immune responses
    (Applicant Wilhelm, Ph.D., Christoph )
  - The role of cell type-specific type I interferon production in the pathogenesis of systemic autoimmunity
    (Applicant Behrendt, Rayk )
- Completed projects
Clinical Research Units
- Completed projects
  - Einsatz immunstimulatorischer Oligonukleotide im enteralen Immunsystem
    (Applicant Hartmann, Gunther )
  - Immune biomarker- and microRNA-guided dose escalation phase I clinical study of a RIG-Iigand for the treatment of multiple sclerosis
    (Applicant Hartmann, Gunther )
Priority Programmes
- Completed projects
Collaborative Research Centres
- Current projects
  - Metabolic characterization of innate lymphoid cells in small cell lung cancer
    (Project Head Surace, Ph.D., Laura )
  - Metabolic regulation of NK cells during metaflammation
    (Project Head Surace, Ph.D., Laura )
  - Metaflammation induced alterations in eosinophil-Treg cell crosstalk in the gonadal white adipose tissue
    (Project Heads Beyer, Marc ; Diny, Ph.D., Nicola Laura )
  - The function of immune cells-intrinsic anabolic lipid metabolism in the progression of metaflammation
    (Project Head Wilhelm, Ph.D., Christoph )
- Completed projects
  - Activation modes of RIG-I
    (Project Heads Hartmann, Gunther ; Schlee, Martin )
  - Antigen-unabhängige Regulation der Effektorfunktion von NKT-Zellen und CD8 T-Zellen durch die plasmazytoide dendritische Zelle
    (Project Head Hartmann, Gunther )
  - Local control of melanocyte-specific CD4+ T cell effector functions in melanomas
    (Project Heads Barchet, Winfried ; Tüting, Thomas )
  - Oligonucleotide-based chemical and immunomodulation of local liver infection
    (Project Head Hartmann, Gunther )
  - Oxidatively modified DNA as immune adjuvant and autoimmune trigger in the skin
    (Project Head Barchet, Winfried )
  - Physiological role of oxidized DNA recognition in the cytosol
    (Project Head Barchet, Winfried )
  - Retinoic acid inducible gene I (RIG-I) in tumor biology: RIG-I-induced exosomes in the tumor mi-croenvironment
    (Project Head Hartmann, Gunther )
  - Systematic Profiling of Genetic Components of Inflammasome Activation during Metaflammation
    (Project Head Schmid-Burgk, Jonathan Leo )
Research Fellowships
- Completed projects
  - Metabolic regulation of epigenetic asymmetry in CD8 T lymphocytes
    (Applicant Liedmann, Swantje )
CRC/Transregios
- Current projects
  - Central tasks of the Collaborative Research Centre
    (Project Heads Hartmann, Gunther ; Hornung, Veit )
  - Dissecting immune sensing of viral RNA at the insect-vertebrate barrier to guide improved messenger RNA vaccine design
    (Project Heads Hartmann, Gunther ; Kümmerer, Beate ; Schlee, Martin )
  - Higher-order structures of ligand bound RIG-I and cGAS
    (Project Heads Geyer, Matthias ; Schlee, Martin )
  - Mobile genetic elements as sources of endogenous immune-stimulatory nucleic acids
    (Project Head Behrendt, Rayk )
  - Role of self RNA in immune sensing and tolerance
    (Project Heads Bauer, Stefan ; Zillinger, Thomas )
  - Systematic dissection of cytosolic DNA sensing and signalling with nanobodies and proteomics
    (Project Heads Hartmann, Gunther ; Meissner, Felix ; Schmidt, Florian Ingo )
  - The innate immune sensors RIG-I and MDA5 in aortic inflammation and calcification
    (Project Head Hartmann, Gunther )
  - TRR 237: Nucleic Acid Immunity
    (Spokespersons Hartmann, Gunther ; Hornung, Veit )
Reinhart Koselleck Projects
- Current projects
  - Feeding the microbiome in infection-induced anorexia
    (Applicant Wilhelm, Ph.D., Christoph )
Emmy Noether Independent Junior Research Groups
- Completed projects
  - Immunorecognition of viral nucleic acids in the cytosol
    (Applicant Barchet, Winfried )
Clinical Trials
- Completed projects
  - Evaluation of novel serological markers for early diagnosis of colorectal neoplasia SID 85
    (Applicant Brenner, Hermann )
International Research Training Groups
- Completed projects
  - GRK 2168: Myeloid antigen presenting cells and the induction of adaptive immunity
    (Spokesperson Kurts, Christian )
Clusters of Excellence
- Completed projects
  - EXC 1023: ImmunoSensation: The Immune Sensory System
    (Spokesperson Hartmann, Gunther )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2151: ImmunoSensation2 - the immune sensory system
    (Spokespersons Hartmann, Gunther ; Kolanus, Waldemar ; Latz, Eicke ; Schultze, Joachim L. )

© 2025 DFG Disclaimer / Copyright / Privacy Policy