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Institution
Universität Leipzig
Biotechnologisch-Biomedizinisches Zentrum
Institut für Bioanalytische Chemie
Address
Deutscher Platz 5
04103 Leipzig
Deutschland
GERiT
This institution in GERiT
04103 Leipzig
Projects
Priority Programmes
Completed projects
Synthese, NMR-spektroskopische und röntgenstrukturanalytische Charakterisierung von P-funktionalisierten Phosphiden der Alkalimetalle, Erdalkalimetalle und des Aluminiums
(Applicant
Hey-Hawkins, Evamarie
)
Research Grants
Current projects
Development of carborane-based selective histone deacetylase inhibitors
(Applicants
Hansen, Finn Kristian
;
Hey-Hawkins, Evamarie
)
Investigation of the antifungal activity and mode of action of proline-rich antimicrobial peptides against Cryptococcus neoformans and Cryptococcus gattii
(Applicant
Brakel, Alexandra
)
Completed projects
Carborane-Containing Cyclooxygenase Inhibitors
(Applicant
Hey-Hawkins, Evamarie
)
Development of carborane-based COX-2 inhibitors for theranostic approaches
(Applicants
Hey-Hawkins, Evamarie
;
Pietzsch, Jens
)
Development of inhibitors of the protein-protein interaction domain of the transcription factor STAT4
(Applicant
Berg, Thorsten
)
Hybrid C3-symmetric Tris-phosphane Ligands with Redox-switchable Backbone
(Applicant
Hey-Hawkins, Evamarie
)
Kristallstrukturanalyse der 4-alpha-Glucanotransferase (D-Enzym) aus Thermus aquaticus: Funktion und Katalysemechanismus des Enzyms im Stärke-Metabolismus und in der Synthese von Cycloamylosen
(Applicant
Sträter, Norbert
)
Mechanisms of activation of the NLRP3 Inflammasome by extracellular calcium ions
(Applicants
Sträter, Norbert
;
Wagner, Ulf
)
Molecular design of novel luminescent complexes based on hybrid phosphine ligands for chemo- and biosensing applications
(Applicant
Hey-Hawkins, Evamarie
)
Oligophosphanide als Bausteine für phosphorreiche Komplexe und Heterocyclen
(Applicant
Hey-Hawkins, Evamarie
)
P-H-funktionalisierte Phosphinocyclopentadiene - Synthese, Strukturen und Ligandeneigenschaften
(Applicant
Hey-Hawkins, Evamarie
)
Raumstruktur und Funktion der eukaryotischen, hetero-oligomeren 6-Phosphofructokinase aus Pichia pastoris (PpPfk)
(Applicant
Sträter, Norbert
)
Stabilisation of low-coordinate phosphorus compounds in transition metal complexes and their reactivity
(Applicant
Hey-Hawkins, Evamarie
)
Stimuli-responsive dendrimers. Towards tunable catalysts (DENDSWITCH)
(Applicant
Hey-Hawkins, Evamarie
)
Structure and function of ecto-nucleotidases in purinergic signaling
(Applicant
Sträter, Norbert
)
Strukturelle Grundlagen und katalytische Funktion der Domänenbewegung der 5'-Nukleotidase
(Applicant
Sträter, Norbert
)
Struktur und Funktion von Ecto-Nukleotidasen in der purinergen Signaltransduktion
(Applicant
Sträter, Norbert
)
Synthese, NMR-spektroskopische und röntgenstrukturanalytische Charakterisierung und Reaktivität von Verbindungen mit Übergangsmetall-Aluminium-Bindungen
(Applicant
Hey-Hawkins, Evamarie
)
Synthese und Reaktivität von Phosphacyclopentadienid-Anionen
(Applicant
Hey-Hawkins, Evamarie
)
Synthesis of P-Chiral Phosphanes from Low-Coordinate Phosphorus Compounds as Bidentate Ligands in Stereoselective Catalysis
(Applicants
Hey-Hawkins, Evamarie
;
de Vries, Johannes Gerardus
)
Untersuchungen von Struktur-Funktions-Beziehungen an nativen und künstlichen dinuklearen Metallenzymen
(Applicant
Sträter, Norbert
)
Research Units
Completed projects
FOR 2149: Elucidation of Adhesion-GPCR Signalling
(Spokesperson
Langenhan, Tobias
)
Human 5'-NT und P2X receptors: Structure, function and inhibitor design
(Applicant
Sträter, Norbert
)
Structural studies on extracellular adhesion GPCR signaling
(Applicants
Schöneberg, Torsten
;
Sträter, Norbert
)
Collaborative Research Centres
Current projects
Enzymology of autoproteolysis and signaling function of the GAIN domain in adhesion GPCRs
(Project Heads
Langenhan, Tobias
;
Sträter, Norbert
)
Completed projects
Identification of molecular mechanisms and druggable targets for the treatment of obesity
(Project Heads
Meiler, Jens
;
Sträter, Norbert
)
Structural Studies on Adipokines and Other Proteins Related to Obesity
(Project Head
Sträter, Norbert
)
Structure and allosteric conformations of eucaryotic 6-phosphofructokinases
(Project Heads
Schöneberg, Torsten
;
Sträter, Norbert
)
Struktur und Funktion eines biologischen Wasserstoffsensors mit NiFe-Kofaktor
(Project Head
Sträter, Norbert
)
Major Research Instrumentation
Completed projects
Röntgeneinkristalldiffraktometer
Research Training Groups
Completed projects
GRK 378: Mechanisms and Applications of Non-Conventional Oxidation Reactions
(Spokesperson
Hey-Hawkins, Evamarie
)
Graduate Schools
Completed projects
GSC 185: Leipzig School of Natural Sciences - Building with Molecules and Nano-objects (BuildMoNa)
(Spokesperson
Hey-Hawkins, Evamarie
)
Additional Information
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