Project Details

Professor Dr. Ari Waisman

Address Johannes Gutenberg-Universität Mainz
Universitätsmedizin
Institut für Molekulare Medizin
Langenbeckstraße 1
55131 Mainz

Projects

As Applicant
- Current projects
  - TRACINg: T-Cell Reactivation by Antigen Presenting Cells In the Central Nervous System (Reinhart Koselleck Projects)
  - The deubiquitinating enzymes CYLD and A20 as gate keepers of central nervous system homeostasis (Priority Programmes)
- Completed projects
  - The role of Fas and IL-6 in experimental autoimmune encephalomyelitis (Research Grants)
  - Zelluläre Quellen und funktionelle Signifikanz von IL-6 bei der Entstehung autoreaktiver T Zell-Antworten im peripheren Immunkompartiment und im zentralen Nervensystem (Research Grants)
  - Role and Function of Microglia Cells in Autoimmune CNS Inflammation (Research Units)
  - The role of CXCR2-ligands for neutrophil mobilization from the bone marrow to peripheral sites (Priority Programmes)
  - Regulatory T Cells and Th17 Cells in Autoimmune Brain Inflammation (Research Grants)
  - The role of IL-1 signaling in the regulation of microglia development and function (Research Grants)
  - The role of ILC3 in autoimmune inflammation (Priority Programmes)
As Spokesperson
- Current projects
  - TRR 355: Heterogeneity and functional specialization of regulatory T cells in distinct microenvironments (CRC/Transregios)
As Participating Researcher
- Completed projects
  - GRK 1043: Antigen-specific Immuntherapy (Research Training Groups)
As Project Head
- Current projects
  - Interplay between pro-inflammatory cytokines and chromatin-remodeling enzymes in the regulation of central nervous system demyelination and repair (CRC/Transregios)
  - Role of IL-6 in shaping local immune milieus in the CNS (CRC/Transregios)
  - Mechanisms controlling Th17 and regulatory T cells in the anti-Leishmania response (Collaborative Research Centres)
  - The role of non-canonical NF-κB signaling in Treg cells in tissue homeostasis and disease (CRC/Transregios)
  - In situ reprogramming of dendritic cells for immunomodulation of CNS-specific Foxp3+ regulatory T cells (CRC/Transregios)
  - Central Tasks (CRC/Transregios)
  - Myeloid cell mediated vascular inflammation in psoriasis (CRC/Transregios)
- Completed projects
  - Using conditional gene targeting to study apoptotic and inflammatory signals in a mouse model for multiple sclerosis (Collaborative Research Centres)
  - The role of CYLD as a tumor suppressor gene (Collaborative Research Centres)
  - Zentraler Zuständigkeitsbereich Versuchstiereinrichtung (Collaborative Research Centres)
  - The role of antigen presenting cells in tolerance and pathogenicity of CD8+ T cells during viral and parasitic infection (Collaborative Research Centres)
  - Regulatory T Cells and Th17 Cells in Autoimmune Brain Inflammation (CRC/Transregios)
  - Genetic Manipulation of Mice and Generation of Humanized Mice (CRC/Transregios)
  - Targets and mediators of IL-17 in mouse models of psoriasis and skin infection (CRC/Transregios)
As Participating Person
- Completed projects
  - Relevance of osteal macrophages in bone remodeling (Priority Programmes)

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Professor Dr. Ari Waisman

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Ari Waisman

Additional Information

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