Project Details

Professor Dr. Christian Reinhardt

Address Universitätsklinikum Essen
Zentrum für innere Medizin
Klinik für Hämatologie und Stammzelltransplantation
Hufelandstraße 55
45147 Essen

Projects

As Applicant
- Completed projects
  - Identifikation von PIK1 Substrat interagierenden phosphopeptidbindenden Domänen und Proteinen (Research Fellowships)
  - In vivo Charakterisierung der Protein Kinase MK2 als potenzielles Zielmolekül für eine neue Chemotherapie-sensitivierende Krebstherapie (Independent Junior Research Groups)
  - Dual checkpoint blockade for the treatment of KRAS- or BRAF-driven neoplastic disease (Research Grants)
  - Development of synergistic combination regimens for the treatment of chemotherapy-resistant high-risk CLL (Clinical Research Units)
  - Coordination and administration of the Clinical Research Unit (Clinical Research Units)
  - Understanding mechanisms of drug resistance and clonal evolution in diffuse large B cell lymphoma (Research Grants)
  - Using mouse models to identify actionable molecular liabilities in Cluster 5 DLBCL (Research Grants)
As Leader
- Completed projects
  - KFO 286: Exploiting Defects in the DNA Damage Response for the Treatment of Chronic Lymphocytic Leukemia (Clinical Research Units)
As Project Head
- Current projects
  - Targeting oncogene-induced DNA repair pathway switches (Collaborative Research Centres)
  - Using autochthonous mouse models of aggressive lymphoma to systematically distill actionable vulnerabilities (Collaborative Research Centres)
  - Identification and characterization of molecular vulnerabilities in SCLC (Collaborative Research Centres)
- Completed projects
  - Phosphorylation-dependent regulation of AATF controls p53-dependent apoptosis in the UV-induced DNA damage response of the skin (Collaborative Research Centres)
  - MK2-dependent cytokine release in the tumor microenvironment (Collaborative Research Centres)
  - Harnessing molecular vulnerabilities to promote an antitumor immune microenvironment (Collaborative Research Centres)
As Co-Investigator
- Completed projects
  - Long-read sequencing of SF3B1 mutated and wildtype chronic lymphocytic leukemia and myelodysplastic syndrome to identify mechanisms of genomic instability and therapy resistance and their impact on prognosis. (Research Grants)

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Professor Dr. Christian Reinhardt

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Christian Reinhardt

Additional Information

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