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- Newly published projects in September 2023
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Bio-dynamic monitoring, diagnosis and follow-up of Abdominal Aortic Aneurysms using optical imaging techniques
Applicants Hans-Henning Eckstein , Daniel J. Rixen
Subject Area Applied Mechanics, Statics and Dynamics
DFG Programme Research Grants Term Since 2023
Abdominal aortic aneurisms (AAA) is a localized balloon-like dilation of the abdominal aorta. It accounts for the death of
at least 45 individuals per 100,000 ...
Applicants Luca Bertinetti , Simone Mattei
Subject Area Structural Biology
Subproject of SPP 2416
DFG Programme Priority Programmes Term Since 2023
Complex carbohydrates are important biopolymers fulfilling a myriad of different biochemical and structural functions across
all kingdoms of life. Chitin is ...
Applicant Allison Groseth
Subject Area Virology
DFG Programme Research Grants Term Since 2023
Arenaviruses are important causes of severe human disease, including hemorrhagic fever (HF), for which few treatments are
currently available. Interestingly, ...
Applicant Jan J. Weigand
Subject Area Inorganic Molecular Chemistry - Synthesis and Characterisation
DFG Programme Reinhart Koselleck Projects Term Since 2023
The current depletion of available primary phosphorus resources is extremely worrying, which is why the EU has included phosphate
rock and elemental phosphorus
Applicants Holger Bettinger , Lars Wesemann
Subject Area Inorganic Molecular Chemistry - Synthesis and Characterisation
DFG Programme Research Grants Term Since 2023
In a joint project of the Bettinger and Wesemann working groups chemistry of low valent borylenes in matrices and solution
as well as stabilized in ...
CADD-SV – Scoring functional effects and deleteriousness of structural variants using machine learning
Applicant Martin Kircher
Subject Area Bioinformatics and Theoretical Biology
DFG Programme Research Grants Term Since 2023
In light of recent advances in structural variant (SV) detection and the study of regulatory genome architectures, we propose
a computational approach to ...
Applicants Florian Eßer , Gunther Graßhoff , Dominik Krinninger
Subject Area Educational Research on Socialization, Welfare and Professionalism
DFG Programme Research Grants Term Since 2023
While for some time after-school child care centers (that in German are referred to as “Hort”) were being considered as outdated
in educational science as well
Care coordination in children and adolescents living with a rare disease - influencing factors and concept review
Applicant Laura Inhestern
Subject Area Public Health, Healthcare Research, Social and Occupational Medicine
DFG Programme Research Grants Term Since 2023
About 6-8% of the population are affected by a rare disease. A disease is considered rare if 5 people or less of 10.000 people
are affected. The majority of ...
CAR T cell micropharmacies: Antigen-induced secretion of soluble VEGFR2 inhibitor for effective T cell invasion into solid cancers
Applicants Sareetha Kailayangiri , Claudia Rössig
Subject Area Pediatric and Adolescent Medicine
DFG Programme Research Grants Term Since 2023
Major barriers for effective targeting of solid tumors by chimeric antigen receptor (CAR) engineered T cells are the lack
of T cell trafficking into the tumor ...
Applicant Cornelius Torp ( in cooperation with Gerda Reith, Sytze F. Kingma )
Subject Area Modern and Contemporary History
DFG Programme Research Grants Term Since 2023
The research project explores the history of gambling in the casinos and gambling halls of the Federal Republic of Germany
since the mid-twentieth century. ...
Applicant Lars Nitschke
Subject Area Immunology
Subproject of FOR 5560
DFG Programme Research Units Term Since 2023
Humoral immune responses are performed by antibodies, which mature in so-called germinal centres, which are specialised structures
in spleen and lymph nodes. ...
Changes in µ-opioid receptor phosphorylation during chronic opioid administration and their pharmacological influence
Applicant Andrea Kliewer
Subject Area Pharmacology
DFG Programme Research Grants Term Since 2023
Opioids such as morphine and fentanyl mediate their effects via the μ-opioid receptor (MOP) and are the cornerstone of therapy
for treatment of chronic pain. ...
Characterization of checkpoint receptor-mediated B-T-cell communication as novel targets for immunotherapies
Applicants Thomas Dörner , Birgit Sawitzki , Franziska Scheibe
Subject Area Molecular and Cellular Neurology and Neuropathology
Subproject of KFO 5023
DFG Programme Clinical Research Units Term Since 2023
This project will perform deep clinical and immunological phenotyping of two antibody-mediated neurological diseases, such
as autoimmune encephalitis (AIE) and
Applicants Uta Elisabeth Höpken , Adrian Schreiber
Subject Area Nephrology
DFG Programme Research Grants Term Since 2023
This project focuses on the development of a novel treatment strategy for ANCA-associated vasculitides (AAV). AAV is an autoimmune
disease in which different ...
Chitin oligosaccharide recognition by human chitinase-like proteins: Deciphering CodeChi at the atomistic level and its impact on cellular signaling
Applicants Jonathan Cramer , Holger Gohlke
Subject Area Biophysics
Subproject of SPP 2416
DFG Programme Priority Programmes Term Since 2023
Chitin and chitosan polymers are recognized as markers of infection by the human immune system. Dysregulation of these proteins
has been linked to ...
Applicant Thomas Bläsius
Subject Area Theoretical Computer Science
DFG Programme Research Grants Term Since 2023
The core difference between theory and practice in the area of algorithmics is that theoretical analysis typically aims to
obtain guarantees that hold for any ...
Applicant Marco Steinhauser
Subject Area General, Cognitive and Mathematical Psychology
DFG Programme Research Grants Term Since 2023
When errors occur in speeded choice tasks, these errors can be reported with a high reliability and within the fraction of
a second. This so-called error ...
Applicant David Izydorczyk
Subject Area General, Cognitive and Mathematical Psychology
DFG Programme Research Grants Term Since 2023
How severe is the condition of this patient? What is the monetary value of this real estate? How much insulin should I take
for this meal? Estimating ...
Cologne Coin Research Portal - Refined Scientific Indexing and Interactive Presentation of a Core Collection for Roman Ancient Egypt
Applicants Gregor Staab , Andreas Weber
Subject Area Ancient History
DFG Programme Cataloguing and Digitisation Term Since 2023
The Coin Collection of the Institute of Classical Studies at the University of Cologne has gained the status of a scientific
Core Collection through a donation
Applicants Erich Bornberg-Bauer , Barbara Feldmeyer , Susanne Foitzik , Jürgen Heinze
Subject Area Evolution, Anthropology
DFG Programme Research Grants Term Since 2023
This project aims to unravel the genomic basis underlying the remarkable, repeated transitions to slave-making in ants. The
slave-makers and their hosts are in
Composition and functional heterogeneity of naïve-like T cells in primary sclerosing cholangitis (PSC)
Applicant Dorothee Schwinge
Subject Area Gastroenterology
DFG Programme Research Grants Term Since 2023
Primary sclerosing cholangitis (PSC) is an enigmatic liver disease characterized by a chronic inflammation leading to scarring
and obliteration of intra- and ...
Applicant Moritz Zaiss
Subject Area Medical Physics, Biomedical Technology
Subproject of FOR 5534
DFG Programme Research Units Term Since 2023
This project is part of the research unit “Fast Mapping of Quantitative MR biosignatures at Ultra-high Magnetic Field”. It
focuses on extending, accelerating, ...
Applicant Dominic Breit
Subject Area Mathematics
Subproject of SPP 2410
DFG Programme Priority Programmes Term Since 2023
We consider the isentropic compressible Euler equations in multi-dimensions with stochastic perturbation of transport type.
The interplay of hyperbolic ...
Leader Halyna Shcherbata
Review Board Basic Research in Biology and Medicine
DFG Programme Major Research Instrumentation Term in 2023
Our group is new to the MHH; hence it is essential that we equip our lab with the equipment necessary to continue performing
cutting-edge research. We use the ...
Conformational adaptation of the microtubule lattice to mechanical forces and biochemical interactions.
Applicant Serapion Pyrpassopoulos
Subject Area Biophysics
DFG Programme Research Grants Term Since 2023
Microtubules are cytoskeletal filaments that span the cell and, among other functions, provide tracks for molecular motor
proteins (motors). Since microtubules