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Institution
Universitätsklinikum Bonn (AöR)
Universitäts-Augenklinik Bonn
Address
Ernst-Abbe-Straße 2
53127 Bonn
Deutschland
GERiT
This institution in GERiT
53127 Bonn
Projects
Priority Programmes
Completed projects
Adaptive optics imaging and micro-stimulation to yield in vivo single-cell biomarker of retinal function and dysfunction in the human retina.
(Applicant
Harmening, Wolf
)
Barrier free chromatic pupillometry in children from infancy on. A novel biomarker to quantify outer and inner retinal function in inherited retinal disorders as a measure of therapeutic benefit after gene therapy.
(Applicant
Lorenz, Birgit
)
Effects of lipofuscin accumulation on lysosomal functions of human RPE cells
(Applicant
Kopitz, Jürgen
)
Fundus Autofluorescence imaging in Age-related Macular degeneration (FAM-Study) using confocal scanning laser ophthalmoscopy
(Applicant
Holz, Frank G.
)
Fundus Autofluorescence imaging in Age-related Macular degeneration (FAM-Study) using confocal scanning laser ophthalmoscopy
(Applicant
Foja, Christian
)
Pathway engineering to optimize homology dependent therapeutic genome editing at the ABCA4 locus in photoreceptors
(Applicants
Busskamp, Volker
;
Stieger, Knut
)
SPP 1088: Age-Related Macular Degeneration
(Spokesperson
Kirchhof, Bernd
)
Symposia, workshops, and sabbaticals of the Priority Program "Age-Related Macular Degeneration
(Applicant
Kirchhof, Bernd
)
Symposia, workshops, and sabbaticals of the Priority Program "Age-Related Macular Degeneration"
(Applicant
Holz, Frank G.
)
Research Grants
Current projects
Advanced Human Stem Cell-Derived Macula Models to Counteract Blindness
(Applicant
Busskamp, Volker
)
Appearance of cone-resolved retinal stimulation and the compression of visual information
(Applicant
Harmening, Wolf
)
Developing a molecular surgical approach to repair and stabilize cone function in retinitis pigmentosa
(Applicant
Busskamp, Volker
)
In vivo mapping of foveal photoreceptors in retinal health and disease
(Applicant
Harmening, Wolf
)
Maintaining retinal ganglion cells within human retinal organoids by implementing a vascular system.
(Applicant
Busskamp, Volker
)
Natural History and Structural Consequences of a Diseased Bruch’s Membrane in Pseudoxanthoma Elasticum (PXE)
(Applicant
Pfau, Kristina
)
Completed projects
Analyse der retinalen Langzeitmorbidität bei ehemaligen Extremfrühgeborenen in Abhängigkeit vom Stadium der Frühgeborenenretinopathie. Eine prospektive explorative Kohortenstudie mittels morphologischer und funktioneller in vivo Diagnostik
(Applicant
Lorenz, Birgit
)
Bilateral cataract following unilateral exposure to ultraviolet radiation. Ocular immune cross-talk and immunmodulation between left and right eye.
(Applicants
Meyer, Ph.D., Linda Maren
;
Wegener, Alfred
)
Das Okulo-Aurikulo-Vertebrale Spektrum (OAVS) - Klinische Aufarbeitung und molekulargenetische Analyse eines heterogenen Krankheitsspektrums
(Applicant
Lorenz, Birgit
)
Deciphering the elemental building blocks of visual appearance
(Applicant
Harmening, Wolf
)
Laser System for Optogenetic Stimulation for the subcellular investigation of Neural Networks
(Applicants
Busskamp, Volker
;
Czarske, Jürgen W.
)
Longitudinal Genotype-Phenotype Correlation in Congenital and Early Onset Hereditary Retinal Degenerations as a Prerequisite for Future Gene Therapeutic Studies.
(Applicant
Lorenz, Birgit
)
Morphologic and functional characterization of macular telangiectasia type 2
(Applicant
Tzaridis, Simone
)
Mutual influence of tumor cells, extracellular matrix and macrophages in intraocular murine melanoma
(Applicant
Herwig-Carl, Martina
)
Verbesserte Früherkennung von Augenhintergrundveränderungen bei Frühgeborenen und Neugeborenen mit perinatalen Erkrankungen zur Verhütung schwerer Sehstörungen bis hin zur Blindheit und zur Optimierung neonatologischer und neuropädiatrischer Maßnahmen
(Applicant
Lorenz, Birgit
)
Emmy Noether Independent Research Groups
Completed projects
Advanced adaptive optics instrumentation for ophthalmic imaging and function testing: the single cell approach to visual function and dysfunction
(Applicant
Harmening, Wolf
)
Return Grant
Completed projects
WBP-Rückkehrstipendium
(Applicant
Larsen, Petra
)
Research Fellowships
Completed projects
Deep-learning based phenotyping and prediction of disease progression in geographic atrophy secondary to age-related macular degeneration
(Applicant
Pfau, Maximilian
)
Investigation of long-wavelength fundus autofluorescence
(Applicant
Gliem, Martin
)
In vivo- and in vitro-investigations regarding the impact of hypoxia on ocular tumors (retinoblastoma and melanoma) in correlation to tumor cell motility.
(Applicant
Herwig-Carl, Martina
)
Local dysregulation of the alternative complement pathway in retinal pigment epithelium as a model for age-related macular degeneration
(Applicant
Herrmann, Philipp
)
Multimodal imaging, packing geometry and autofluorescence properties of human retinal pigment epithelium cells as a function of age and age-related macular degeneration
(Applicant
Ach, Thomas
)
Probing retinal and neural mechanisms of vision by hyperacute optical stimulation of single photoreceptor cells
(Applicant
Harmening, Wolf
)
Fellowship
Completed projects
Microstructural determinants of dark adaptation and effects of retinoid administration in age-related macular degeneration
(Applicant
Pfau, Kristina
)
Structure function correlation of high resolution retinal imaging in early age-related macular degeneration and physiological aging
(Applicant
Goerdt, Lukas
)
The associations of inflammation biomarkers with the risk of developing age-related macular degeneration
(Applicant
Larsen, Petra
)
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