Project Details

Professorin Ingrid Fleming, Ph.D.

Address Goethe-Universität Frankfurt am Main
Universitätsklinikum
Zentrum für Molekulare Medizin
Vascular Research Center
Theodor-Stern-Kai 7
60596 Frankfurt am Main

Projects

As Applicant
- Current projects
  - Deciphering the role of soluble epoxide hydrolase in homeostasis with Chemical Biology tools (Research Grants)
- Completed projects
  - Angiotensin converting enzyme (ACE): defining its role as a signal transduction molecule (Research Units)
  - General costs relating the administration of the Research Unit (Research Units)
  - Vascular complications of type 2 diabetes: tyrosine phosphorylation of the endothelial nitric oxide synthase (eNOS) (Research Grants)
  - Angiotensin converting enzyme (ACE): regulation and dysregulation (Research Grants)
  - Identification of a G protein-coupled receptor for 11(R),12(S)-epoxyeicosatrienoic acid and its effects in the cardiovascular system (Research Grants)
As Spokesperson
- Completed projects
  - FOR 501: Vascular Homeostasis: Molecular Mechanisms and Cellular Mediators (Research Units)
  - SFB 834: Endothelial Signalling and Vascular Repair (Collaborative Research Centres)
As Participating Researcher
- Current projects
  - EXC 2026: Cardio-Pulmonary Institute (CPI) (Clusters of Excellence (ExStra))
  - GRK 2336: Resolution of inflammation – Mediators, signaling and therapeutic options (Research Training Groups)
- Completed projects
  - GRK 757: Roles of Eicosanoids in Biology and Medicine (International Research Training Groups)
  - EXC 147: Cardio-Pulmonary System (Clusters of Excellence)
As Project Head
- Current projects
  - Role of the cytochrome P450-soluble epoxide pathway in the regulation of lymphangiogenesis (Collaborative Research Centres)
  - Endothelial-pericyte metabolic communication in damage control (Collaborative Research Centres)
  - Mass spectrometry platform (Collaborative Research Centres)
  - Integrated research training group (Collaborative Research Centres)
  - The impact of oxidative post-translational modifications on vascular function and angiocrine signaling (Collaborative Research Centres)
  - Microproteins encoded by “non-coding” RNAs in vascular disease (CRC/Transregios)
- Completed projects
  - eNOS in endothelial Cells and Platelets: Determining the "Phsopho-Switch" for eNOS uncoupling (Collaborative Research Centres)
  - Activation and Expression of eNOS: Molecular Mechanisms of Mechanotransduction (Collaborative Research Centres)
  - A Kinase anchoring proteins (AKAPs) in endothelial signalling (Collaborative Research Centres)
  - The Cytochrome P450/soluble epoxide hydrolase axis in angiogenic endothelial cell signalling and vascular differentiation (CRC/Transregios)
  - PYK2-dependent eNOS tyrosine phosphorylation and its role in signalling, disease and repair (Collaborative Research Centres)
  - Functional consequences of a redox regulated activation of calpain in diabetes (Collaborative Research Centres)
  - The effect of AMP-activated protein kinase on endothelial energy metabolism and the consequences for angiogenesis and signalling (Collaborative Research Centres)
  - The role of the soluble epoxide hydrolase in the regulation of vascular stability/integrity (Collaborative Research Centres)
  - Central Tasks of the Collaborative Research Centre (Collaborative Research Centres)

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Professorin Ingrid Fleming, Ph.D.

Additional Information

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Professorin Ingrid Fleming, Ph.D.

Additional Information

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