SFB 1744:  Compartmentalized cellular networks in neurovascular diseases

• Subject Area: Medicine
• Term: since 2026
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 548585053

No abstract available

• DFG Programme: Collaborative Research Centres

Current projects

• A01 - Arterial aging as a target for lowering the burden of cerebral small vessel disease (Project Heads Beaufort, Nathalie ;  Georgakis, Ph.D., Marios )
• A02 - Zonation-specific endothelial FOXF2 signaling in stroke and small vessel disease (Project Head Dichgans, Martin )
• A03 - Investigating the role of FOXF2 in regulating the neurovascular compartment using a human iPSC-based 3D BBB model. (Project Head Paquet, Dominik )
• A04 - Probing tissue replacement strategies as a therapeutic intervention to facilitate restoration of the peri-infarct region after stroke (Project Heads Schäfer, Simon T. ;  Wahl, Ph.D., Anna-Sophia )
• A05 - Vascular multi-cellular circadian networks as a modulator of stroke progression (Project Heads Robles, Maria ;  Tiedt, Ph.D., Steffen )
• A06 - Compartmentalized diversity of inflammatory GPCR networks in neurovascular disease (Project Heads Bernhagen, Jürgen ;  Steffens, Sabine )
• A07 - Bioenergetic failure of neuro-glial cell networks in small vessel pathology (Project Heads Dichgans, Martin ;  Misgeld, Thomas )
• B01 - Vascular zonation-specific mechanisms of the post-stroke vascular-microglia interaction (Project Head Liesz, Arthur )
• B02 - Deciphering the role of perivascular inflammation after subarachnoid haemorrhage (Project Heads Plesnila, Nikolaus ;  Terpolilli, Nicole )
• B03 - Skull–meninges connections in post-stroke neuroinflammation (Project Heads Ertürk, Ali ;  Hellal, Ph.D., Farida )
• B04 - Molecular and cellular mechanisms of T cell infiltration and activation in the lesion after ischemic stroke (Project Heads Benakis, Corinne ;  Kawakami, Naoto )
• B05 - Interactions between stroke-induced neuroinflammatory responses and human brain reorganization at single-neuron resolution (Project Heads Brendel, Matthias ;  Jacob, Simon N. )
• C01 - Function of astrocytes at the juxtavascular interface in health and disease (Project Head Götz, Magdalena )
• C02 - Role of lipoproteins in cerebral amyloid angiopathy (Project Head Simons, Mikael Jakob )
• C03 - Promoting neuroblast maturation to improve recovery post-stroke (Project Head Ninkovic, Ph.D., Jovica )
• C04 - Defining the interplay of vascular and glial cellular networks in response to neurovascular amyloidosis (Project Heads Neher, Ph.D., Jonas ;  Sirko, Swetlana )
• MGK - Integrated Research Training Group on Neurovascular Disease (IRTG-BrainVasc) (Project Heads Plesnila, Nikolaus ;  Wahl, Ph.D., Anna-Sophia )
• Z01 - Central Tasks (Project Head Dichgans, Martin )
• Z02 - Central project on Multi-omic data integration (Project Heads Simons, Mikael Jakob ;  Spitzer, Hannah )

• Applicant Institution: Ludwig-Maximilians-Universität München
• Participating University: Technische Universität München (TUM)
• Participating Institution: Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt; Bioengineering Center; Institute for Intelligent Biotechnologies
• Spokesperson: Professor Dr. Martin Dichgans